Anti-ADIPO/ ADIPOQ/ ACDC functional antibody
Anti-ADIPO/ ADIPOQ/ ACDC functional antibody for cell culture, ELISA & in-vivo assay
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T15572-Ab-1/ GM-Tg-hg-T15572-Ab-2 | Anti-Human ADIPOQ monoclonal antibody | Human |
GM-Tg-rg-T15572-Ab-1/ GM-Tg-rg-T15572-Ab-2 | Anti-Rat ADIPOQ monoclonal antibody | Rat |
GM-Tg-mg-T15572-Ab-1/ GM-Tg-mg-T15572-Ab-2 | Anti-Mouse ADIPOQ monoclonal antibody | Mouse |
GM-Tg-cynog-T15572-Ab-1/ GM-Tg-cynog-T15572-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ADIPOQ monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T15572-Ab-1/ GM-Tg-felg-T15572-Ab-2 | Anti-Feline ADIPOQ monoclonal antibody | Feline |
GM-Tg-cang-T15572-Ab-1/ GM-Tg-cang-T15572-Ab-2 | Anti-Canine ADIPOQ monoclonal antibody | Canine |
GM-Tg-bovg-T15572-Ab-1/ GM-Tg-bovg-T15572-Ab-2 | Anti-Bovine ADIPOQ monoclonal antibody | Bovine |
GM-Tg-equg-T15572-Ab-1/ GM-Tg-equg-T15572-Ab-2 | Anti-Equine ADIPOQ monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-T15572-Ab-1/ GM-Tg-hg-T15572-Ab-2; GM-Tg-rg-T15572-Ab-1/ GM-Tg-rg-T15572-Ab-2; GM-Tg-mg-T15572-Ab-1/ GM-Tg-mg-T15572-Ab-2; GM-Tg-cynog-T15572-Ab-1/ GM-Tg-cynog-T15572-Ab-2; GM-Tg-felg-T15572-Ab-1/ GM-Tg-felg-T15572-Ab-2; GM-Tg-cang-T15572-Ab-1/ GM-Tg-cang-T15572-Ab-2; GM-Tg-bovg-T15572-Ab-1/ GM-Tg-bovg-T15572-Ab-2; GM-Tg-equg-T15572-Ab-1/ GM-Tg-equg-T15572-Ab-2 |
Products Name | Anti-ADIPOQ monoclonal antibody |
Format | mab |
Target Name | ADIPOQ |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-ADIPOQ benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-T15572-Ag-1 | Recombinant multi-species ADIPO/ ADIPOQ/ ACDC protein |
ORF Viral Vector | vGMAP000564 | Human ADIPOQ Adenovirus particle |
ORF Viral Vector | pGMAP000564 | Human ADIPOQ Adenovirus plasmid |
ORF Viral Vector | pGMAAV000127 | rat Adipoq AAV plasmid |
ORF Viral Vector | pGMLPm001917 | mouse Adipoq Lentivirus plasmid |
ORF Viral Vector | vGMAAV000127 | rat Adipoq AAV particle |
ORF Viral Vector | vGMLPm001917 | mouse Adipoq Lentivirus particle |
Target information
Target ID | GM-T15572 |
Target Name | ADIPOQ |
Gene ID | 9370,11450,246253,574212,403625,554338,282865,100059500 |
Gene Symbol and Synonyms | 30kDa,ACDC,ACRP30,Ad,Adid,adipo,ADIPOQ,ADIPQTL1,ADPN,APM-1,APM1,APN,GBP28 |
Uniprot Accession | Q15848,Q3Y5Z3 |
Uniprot Entry Name | ADIPO_HUMAN,ADIPO_BOVIN |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Category | Therapeutics Target, Diagnostics Biomarker |
Disease | Breast Cancer |
Gene Ensembl | ENSG00000181092 |
Target Classification | N/A |
The target: ADIPOQ, gene name: ADIPOQ, also named as ACDC, ACRP30, ADIPQTL1, ADPN, APM-1, APM1, GBP28. This gene is expressed in adipose tissue exclusively. It encodes a protein with similarity to collagens X and VIII and complement factor C1q. The encoded protein circulates in the plasma and is involved with metabolic and hormonal processes. Mutations in this gene are associated with adiponectin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Apr 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.