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Anti-PRTN3/ ACPA/ AGP7 monoclonal antibody
Anti-PRTN3/ ACPA/ AGP7 antibody for FACS & in-vivo assay
Go to PRTN3/PRTN3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T15882-Ab-1/ GM-Tg-hg-T15882-Ab-2 | Anti-Human PRTN3 monoclonal antibody | Human |
| GM-Tg-rg-T15882-Ab-1/ GM-Tg-rg-T15882-Ab-2 | Anti-Rat PRTN3 monoclonal antibody | Rat |
| GM-Tg-mg-T15882-Ab-1/ GM-Tg-mg-T15882-Ab-2 | Anti-Mouse PRTN3 monoclonal antibody | Mouse |
| GM-Tg-cynog-T15882-Ab-1/ GM-Tg-cynog-T15882-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PRTN3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T15882-Ab-1/ GM-Tg-felg-T15882-Ab-2 | Anti-Feline PRTN3 monoclonal antibody | Feline |
| GM-Tg-cang-T15882-Ab-1/ GM-Tg-cang-T15882-Ab-2 | Anti-Canine PRTN3 monoclonal antibody | Canine |
| GM-Tg-bovg-T15882-Ab-1/ GM-Tg-bovg-T15882-Ab-2 | Anti-Bovine PRTN3 monoclonal antibody | Bovine |
| GM-Tg-equg-T15882-Ab-1/ GM-Tg-equg-T15882-Ab-2 | Anti-Equine PRTN3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T15882-Ab-1/ GM-Tg-hg-T15882-Ab-2; GM-Tg-rg-T15882-Ab-1/ GM-Tg-rg-T15882-Ab-2; GM-Tg-mg-T15882-Ab-1/ GM-Tg-mg-T15882-Ab-2; GM-Tg-cynog-T15882-Ab-1/ GM-Tg-cynog-T15882-Ab-2; GM-Tg-felg-T15882-Ab-1/ GM-Tg-felg-T15882-Ab-2; GM-Tg-cang-T15882-Ab-1/ GM-Tg-cang-T15882-Ab-2; GM-Tg-bovg-T15882-Ab-1/ GM-Tg-bovg-T15882-Ab-2; GM-Tg-equg-T15882-Ab-1/ GM-Tg-equg-T15882-Ab-2 |
| Products Name | Anti-PRTN3 monoclonal antibody |
| Format | mab |
| Target Name | PRTN3 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PRTN3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species PRTN3/ ACPA/ AGP7 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMAP000488 | Human PRTN3 Adenovirus particle |
| ORF Viral Vector | pGMLP000548 | human PRTN3 Lentivirus plasmid |
| ORF Viral Vector | pGMAP000488 | Human PRTN3 Adenovirus plasmid |
| ORF Viral Vector | vGMLP000548 | human PRTN3 Lentivirus particle |
| ORF Viral Vector | pGMLPm001270 | mouse Prtn3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001270 | mouse Prtn3 Lentivirus particle |
Target information
| Target ID | GM-T15882 |
| Target Name | PRTN3 |
| Gene ID | 5657,19152,721131,100298591,100147215 |
| Gene Symbol and Synonyms | ACPA,AGP7,C-ANCA,CANCA,MBN,MBT,mPR3,NP-4,NP4,P29,PR-3,PR3,PRTN3 |
| Uniprot Accession | P24158 |
| Uniprot Entry Name | PRTN3_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Immuno-oncology Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000196415 |
| Target Classification | Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA) |
The target: PRTN3, gene name: PRTN3, also named as ACPA, AGP7, C-ANCA, CANCA, MBN, MBT, NP-4, NP4, P29, PR-3, PR3. Enables enzyme binding activity; serine-type endopeptidase activity; and signaling receptor binding activity. Involved in several processes, including mature conventional dendritic cell differentiation; membrane protein ectodomain proteolysis; and neutrophil extravasation. Located in azurophil granule lumen; cytosol; and plasma membrane raft. Colocalizes with plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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