- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-HS90A/ HSP90A/ HSP90AA1 monoclonal antibody
Anti-HS90A/ HSP90A/ HSP90AA1 antibody for FACS & in-vivo assay
Go to HSP90A/HSP90AA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T18477-Ab-1/ GM-Tg-hg-T18477-Ab-2 | Anti-Human HSP90A/HSP90AA1 monoclonal antibody | Human |
| GM-Tg-rg-T18477-Ab-1/ GM-Tg-rg-T18477-Ab-2 | Anti-Rat HSP90A/HSP90AA1 monoclonal antibody | Rat |
| GM-Tg-mg-T18477-Ab-1/ GM-Tg-mg-T18477-Ab-2 | Anti-Mouse HSP90A/HSP90AA1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T18477-Ab-1/ GM-Tg-cynog-T18477-Ab-2 | Anti-Cynomolgus/ Rhesus macaque HSP90A/HSP90AA1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T18477-Ab-1/ GM-Tg-felg-T18477-Ab-2 | Anti-Feline HSP90A/HSP90AA1 monoclonal antibody | Feline |
| GM-Tg-cang-T18477-Ab-1/ GM-Tg-cang-T18477-Ab-2 | Anti-Canine HSP90A/HSP90AA1 monoclonal antibody | Canine |
| GM-Tg-bovg-T18477-Ab-1/ GM-Tg-bovg-T18477-Ab-2 | Anti-Bovine HSP90A/HSP90AA1 monoclonal antibody | Bovine |
| GM-Tg-equg-T18477-Ab-1/ GM-Tg-equg-T18477-Ab-2 | Anti-Equine HSP90A/HSP90AA1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T18477-Ab-1/ GM-Tg-hg-T18477-Ab-2; GM-Tg-rg-T18477-Ab-1/ GM-Tg-rg-T18477-Ab-2; GM-Tg-mg-T18477-Ab-1/ GM-Tg-mg-T18477-Ab-2; GM-Tg-cynog-T18477-Ab-1/ GM-Tg-cynog-T18477-Ab-2; GM-Tg-felg-T18477-Ab-1/ GM-Tg-felg-T18477-Ab-2; GM-Tg-cang-T18477-Ab-1/ GM-Tg-cang-T18477-Ab-2; GM-Tg-bovg-T18477-Ab-1/ GM-Tg-bovg-T18477-Ab-2; GM-Tg-equg-T18477-Ab-1/ GM-Tg-equg-T18477-Ab-2 |
| Products Name | Anti-HSP90A/HSP90AA1 monoclonal antibody |
| Format | mab |
| Target Name | HSP90A |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-HSP90A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species HS90A/ HSP90A/ HSP90AA1 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLV000214 | human HSP90AA1 Lentivirus particle |
| ORF Viral Vector | pGMLV000214 | human HSP90AA1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm003576 | mouse Hsp90aa1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003576 | mouse Hsp90aa1 Lentivirus particle |
Target information
| Target ID | GM-T18477 |
| Target Name | HSP90A |
| Gene ID | 3320,15519,299331,708431,480438,101094857,281832,100033837 |
| Gene Symbol and Synonyms | 86kDa,89kDa,EL52,HEL-S-65p,Hsp103,hsp4,HSP86,Hsp86-1,Hsp89,HSP89A,Hsp90,HSP90A,HSP90AA1,HSP90N,HSPC1,HSPCA,HSPCAL1,HSPCAL4,HSPN,LAP-2,LAP2 |
| Uniprot Accession | P07900,P82995,Q76LV2,Q9GKX7 |
| Uniprot Entry Name | HS90A_HUMAN,HS90A_RAT,HS90A_BOVIN,HS90A_HORSE |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Diagnostics Biomarker |
| Disease | Lung Cancer, Congenital occlusion of ureteropelvic junction |
| Gene Ensembl | ENSG00000080824 |
| Target Classification | N/A |
The target: HSP90A, gene name: HSP90AA1, also named as EL52, HEL-S-65p, HSP86, HSP89A, HSP90A, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, Hsp103, Hsp89, Hsp90, LAP-2, LAP2. The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
