Anti-SC6A8/ SLC6A8/ CCDS1 monoclonal antibody

Anti-SC6A8/ SLC6A8/ CCDS1 antibody for FACS & in-vivo assay

Target products collectionGo to SLC6A8/SLC6A8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T20741-Ab-1/ GM-Tg-hg-T20741-Ab-2Anti-Human SLC6A8 monoclonal antibodyHuman
GM-Tg-rg-T20741-Ab-1/ GM-Tg-rg-T20741-Ab-2Anti-Rat SLC6A8 monoclonal antibodyRat
GM-Tg-mg-T20741-Ab-1/ GM-Tg-mg-T20741-Ab-2Anti-Mouse SLC6A8 monoclonal antibodyMouse
GM-Tg-cynog-T20741-Ab-1/ GM-Tg-cynog-T20741-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC6A8 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T20741-Ab-1/ GM-Tg-felg-T20741-Ab-2Anti-Feline SLC6A8 monoclonal antibodyFeline
GM-Tg-cang-T20741-Ab-1/ GM-Tg-cang-T20741-Ab-2Anti-Canine SLC6A8 monoclonal antibodyCanine
GM-Tg-bovg-T20741-Ab-1/ GM-Tg-bovg-T20741-Ab-2Anti-Bovine SLC6A8 monoclonal antibodyBovine
GM-Tg-equg-T20741-Ab-1/ GM-Tg-equg-T20741-Ab-2Anti-Equine SLC6A8 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T20741-Ab-1/ GM-Tg-hg-T20741-Ab-2; GM-Tg-rg-T20741-Ab-1/ GM-Tg-rg-T20741-Ab-2;
GM-Tg-mg-T20741-Ab-1/ GM-Tg-mg-T20741-Ab-2; GM-Tg-cynog-T20741-Ab-1/ GM-Tg-cynog-T20741-Ab-2;
GM-Tg-felg-T20741-Ab-1/ GM-Tg-felg-T20741-Ab-2; GM-Tg-cang-T20741-Ab-1/ GM-Tg-cang-T20741-Ab-2;
GM-Tg-bovg-T20741-Ab-1/ GM-Tg-bovg-T20741-Ab-2; GM-Tg-equg-T20741-Ab-1/ GM-Tg-equg-T20741-Ab-2
Products NameAnti-SLC6A8 monoclonal antibody
Formatmab
Target NameSLC6A8
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC6A8 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SC6A8/ SLC6A8/ CCDS1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP004405human SLC6A8 Lentivirus particle
    ORF Viral VectorpGMLP004405human SLC6A8 Lentivirus plasmid
    ORF Viral VectorpGMLPm004178mouse Slc6a8 Lentivirus plasmid
    ORF Viral VectorvGMLPm004178mouse Slc6a8 Lentivirus particle


    Target information

    Target IDGM-T20741
    Target NameSLC6A8
    Gene ID6535,102857,50690,698307,492242,101087976,282367,100058799
    Gene Symbol and SynonymsCCDS1,CHOT1,CHT1,Creat,CRT,CRT-1,CRT1,CRTR,CT1,CTR5,SLC6A8
    Uniprot AccessionP48029,P28570,O18875
    Uniprot Entry NameSC6A8_HUMAN,SC6A8_RAT,SC6A8_BOVIN
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000130821
    Target ClassificationN/A

    The target: SLC6A8, gene name: SLC6A8, also named as CCDS1, CRT, CRTR, CT1, CTR5. The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.