Anti-GPC5D/ GPRC5D monoclonal antibody

Anti-GPC5D/ GPRC5D antibody for FACS & in-vivo assay

Target products collectionGo to GPRC5D/GPRC5D products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T23519-Ab-1/ GM-Tg-hg-T23519-Ab-2Anti-Human GPRC5D monoclonal antibodyHuman
GM-Tg-rg-T23519-Ab-1/ GM-Tg-rg-T23519-Ab-2Anti-Rat GPRC5D monoclonal antibodyRat
GM-Tg-mg-T23519-Ab-1/ GM-Tg-mg-T23519-Ab-2Anti-Mouse GPRC5D monoclonal antibodyMouse
GM-Tg-cynog-T23519-Ab-1/ GM-Tg-cynog-T23519-Ab-2Anti-Cynomolgus/ Rhesus macaque GPRC5D monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T23519-Ab-1/ GM-Tg-felg-T23519-Ab-2Anti-Feline GPRC5D monoclonal antibodyFeline
GM-Tg-cang-T23519-Ab-1/ GM-Tg-cang-T23519-Ab-2Anti-Canine GPRC5D monoclonal antibodyCanine
GM-Tg-bovg-T23519-Ab-1/ GM-Tg-bovg-T23519-Ab-2Anti-Bovine GPRC5D monoclonal antibodyBovine
GM-Tg-equg-T23519-Ab-1/ GM-Tg-equg-T23519-Ab-2Anti-Equine GPRC5D monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T23519-Ab-1/ GM-Tg-hg-T23519-Ab-2; GM-Tg-rg-T23519-Ab-1/ GM-Tg-rg-T23519-Ab-2;
GM-Tg-mg-T23519-Ab-1/ GM-Tg-mg-T23519-Ab-2; GM-Tg-cynog-T23519-Ab-1/ GM-Tg-cynog-T23519-Ab-2;
GM-Tg-felg-T23519-Ab-1/ GM-Tg-felg-T23519-Ab-2; GM-Tg-cang-T23519-Ab-1/ GM-Tg-cang-T23519-Ab-2;
GM-Tg-bovg-T23519-Ab-1/ GM-Tg-bovg-T23519-Ab-2; GM-Tg-equg-T23519-Ab-1/ GM-Tg-equg-T23519-Ab-2
Products NameAnti-GPRC5D monoclonal antibody
Formatmab
Target NameGPRC5D
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GPRC5D benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    BiosimilarGMP-Bios-ab-546Pre-Made Talquetamab biosimilar, Bispecific mAb, Anti-GPRC5D;CD3E Antibody: Anti-T3E/TCRE/IMD18/CD3epsilon therapeutic antibody
    Target AntigenProducts DevelopingMulti-species GPC5D/ GPRC5D VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-T23519
    Target NameGPRC5D
    Gene ID55507,93746,500349,698898,486679,101082499,534963,100066685
    Gene Symbol and SynonymsGPRC5D,RGD1563887
    Uniprot AccessionQ9NZD1
    Uniprot Entry NameGPC5D_HUMAN
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target, Immuno-oncology Target, INN Index
    DiseaseN/A
    Gene EnsemblENSG00000111291
    Target ClassificationCheckpoint-Immuno Oncology, GPCR

    The target: GPRC5D, gene name: GPRC5D, also named as . The protein encoded by this gene is a member of the G protein-coupled receptor family; however, the specific function of this gene has not yet been determined..



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.