- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-IL33/ C9orf26/ DVS27 functional antibody
Anti-IL33/ C9orf26/ DVS27 functional antibody for cell culture, ELISA & in-vivo assay
Go to IL33/IL33 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T23797-Ab-1/ GM-Tg-hg-T23797-Ab-2 | Anti-Human IL33 monoclonal antibody | Human |
| GM-Tg-rg-T23797-Ab-1/ GM-Tg-rg-T23797-Ab-2 | Anti-Rat IL33 monoclonal antibody | Rat |
| GM-Tg-mg-T23797-Ab-1/ GM-Tg-mg-T23797-Ab-2 | Anti-Mouse IL33 monoclonal antibody | Mouse |
| GM-Tg-cynog-T23797-Ab-1/ GM-Tg-cynog-T23797-Ab-2 | Anti-Cynomolgus/ Rhesus macaque IL33 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T23797-Ab-1/ GM-Tg-felg-T23797-Ab-2 | Anti-Feline IL33 monoclonal antibody | Feline |
| GM-Tg-cang-T23797-Ab-1/ GM-Tg-cang-T23797-Ab-2 | Anti-Canine IL33 monoclonal antibody | Canine |
| GM-Tg-bovg-T23797-Ab-1/ GM-Tg-bovg-T23797-Ab-2 | Anti-Bovine IL33 monoclonal antibody | Bovine |
| GM-Tg-equg-T23797-Ab-1/ GM-Tg-equg-T23797-Ab-2 | Anti-Equine IL33 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T23797-Ab-1/ GM-Tg-hg-T23797-Ab-2; GM-Tg-rg-T23797-Ab-1/ GM-Tg-rg-T23797-Ab-2; GM-Tg-mg-T23797-Ab-1/ GM-Tg-mg-T23797-Ab-2; GM-Tg-cynog-T23797-Ab-1/ GM-Tg-cynog-T23797-Ab-2; GM-Tg-felg-T23797-Ab-1/ GM-Tg-felg-T23797-Ab-2; GM-Tg-cang-T23797-Ab-1/ GM-Tg-cang-T23797-Ab-2; GM-Tg-bovg-T23797-Ab-1/ GM-Tg-bovg-T23797-Ab-2; GM-Tg-equg-T23797-Ab-1/ GM-Tg-equg-T23797-Ab-2 |
| Products Name | Anti-IL33 monoclonal antibody |
| Format | mab |
| Target Name | IL33 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-IL33 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Biosimilar | GMP-Bios-ab-591 | Pre-Made Tozorakimab biosimilar, Whole mAb, Anti-IL33 Antibody: Anti-C9orf26/DVS27/IL1F11/NF-HEV/NFEHEV therapeutic antibody |
| Biosimilar | GMP-Bios-ab-588 | Pre-Made Torudokimab biosimilar, Whole mAb, Anti-IL33 Antibody: Anti-C9orf26/DVS27/IL1F11/NF-HEV/NFEHEV therapeutic antibody |
| Biosimilar | GMP-Bios-ab-283 | Pre-Made Itepekimab biosimilar, Whole mAb, Anti-IL33 Antibody: Anti-C9orf26/DVS27/IL1F11/NF-HEV/NFEHEV therapeutic antibody |
| Target Antigen | GM-Tg-g-T23797-Ag-1 | Recombinant multi-species IL33/ C9orf26/ DVS27 protein |
| Cytokine | GM-Tg-g-T23797-Ag-1 | Interleukin 33 (IL33) protein |
| ORF Viral Vector | vGMLV000045 | human IL33 Lentivirus particle |
| ORF Viral Vector | pGMLV000045 | human IL33 Lentivirus plasmid |
| ORF Viral Vector | pGMAAV000250 | house mouse Il33 AAV plasmid |
| ORF Viral Vector | pGMLPm000320 | mouse Il33 Lentivirus plasmid |
| ORF Viral Vector | vGMAAV000250 | house mouse Il33 AAV particle |
| ORF Viral Vector | vGMLPm000320 | mouse Il33 Lentivirus particle |
Target information
| Target ID | GM-T23797 |
| Target Name | IL33 |
| Gene ID | 90865,77125,361749,717301,403810,101093403,507054,100059908 |
| Gene Symbol and Synonyms | 9230117N10Rik,C9orf26,DVS27,Il-33,IL1F11,IL33,NF-HEV,NFEHEV,RGD1311155 |
| Uniprot Accession | O95760,Q66H70,O97863 |
| Uniprot Entry Name | IL33_HUMAN,IL33_RAT,IL33_CANLF |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, INN Index, Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000137033 |
| Target Classification | N/A |
The target: IL33, gene name: IL33, also named as C9orf26, DVS27, IL1F11, NF-HEV, NFEHEV. The protein encoded by this gene is a cytokine that binds to the IL1RL1/ST2 receptor. The encoded protein is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
