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Anti-PRKCQ monoclonal antibody
Pre-made anti-PRKCQ monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to PRKCQ/PRKCQ products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T23995-Ab-1/ GM-Tg-hg-T23995-Ab-2 | Anti-Human PRKCQ monoclonal antibody | Human |
| GM-Tg-rg-T23995-Ab-1/ GM-Tg-rg-T23995-Ab-2 | Anti-Rat PRKCQ monoclonal antibody | Rat |
| GM-Tg-mg-T23995-Ab-1/ GM-Tg-mg-T23995-Ab-2 | Anti-Mouse PRKCQ monoclonal antibody | Mouse |
| GM-Tg-cynog-T23995-Ab-1/ GM-Tg-cynog-T23995-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PRKCQ monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T23995-Ab-1/ GM-Tg-felg-T23995-Ab-2 | Anti-Feline PRKCQ monoclonal antibody | Feline |
| GM-Tg-cang-T23995-Ab-1/ GM-Tg-cang-T23995-Ab-2 | Anti-Canine PRKCQ monoclonal antibody | Canine |
| GM-Tg-bovg-T23995-Ab-1/ GM-Tg-bovg-T23995-Ab-2 | Anti-Bovine PRKCQ monoclonal antibody | Bovine |
| GM-Tg-equg-T23995-Ab-1/ GM-Tg-equg-T23995-Ab-2 | Anti-Equine PRKCQ monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T23995-Ab-1/ GM-Tg-hg-T23995-Ab-2; GM-Tg-rg-T23995-Ab-1/ GM-Tg-rg-T23995-Ab-2; GM-Tg-mg-T23995-Ab-1/ GM-Tg-mg-T23995-Ab-2; GM-Tg-cynog-T23995-Ab-1/ GM-Tg-cynog-T23995-Ab-2; GM-Tg-felg-T23995-Ab-1/ GM-Tg-felg-T23995-Ab-2; GM-Tg-cang-T23995-Ab-1/ GM-Tg-cang-T23995-Ab-2; GM-Tg-bovg-T23995-Ab-1/ GM-Tg-bovg-T23995-Ab-2; GM-Tg-equg-T23995-Ab-1/ GM-Tg-equg-T23995-Ab-2 |
| Products Name | Anti-PRKCQ monoclonal antibody |
| Format | mab |
| Target Name | PRKCQ |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-PRKCQ monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T23995-Ag-1 | Recombinant multi-species KPCT/ PRKCQ/ PRKCT protein |
Target information
| Target ID | GM-T23995 |
| Target Name | PRKCQ |
| Gene ID | 5588,18761,85420,722559,478013,101100730,505901,100070207 |
| Gene Symbol and Synonyms | A130035A12Rik,nPKC-theta,PKC-0,PKC-theta,Pkcq,PKCtheta,PRKCQ,PRKCT |
| Uniprot Accession | Q04759,Q9WTQ0 |
| Uniprot Entry Name | KPCT_HUMAN,KPCT_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000065675 |
| Target Classification | Kinase |
The target: PRKCQ, gene name: PRKCQ, also named as PRKCT, nPKC-theta. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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