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Anti-FFAR1/ GPR40/ FFA1R monoclonal antibody
Anti-FFAR1/ GPR40/ FFA1R antibody for FACS & in-vivo assay
Go to GPR40/FFAR1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T25608-Ab-1/ GM-Tg-hg-T25608-Ab-2 | Anti-Human GPR40/FFAR1 monoclonal antibody | Human |
| GM-Tg-rg-T25608-Ab-1/ GM-Tg-rg-T25608-Ab-2 | Anti-Rat GPR40/FFAR1 monoclonal antibody | Rat |
| GM-Tg-mg-T25608-Ab-1/ GM-Tg-mg-T25608-Ab-2 | Anti-Mouse GPR40/FFAR1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T25608-Ab-1/ GM-Tg-cynog-T25608-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GPR40/FFAR1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T25608-Ab-1/ GM-Tg-felg-T25608-Ab-2 | Anti-Feline GPR40/FFAR1 monoclonal antibody | Feline |
| GM-Tg-cang-T25608-Ab-1/ GM-Tg-cang-T25608-Ab-2 | Anti-Canine GPR40/FFAR1 monoclonal antibody | Canine |
| GM-Tg-bovg-T25608-Ab-1/ GM-Tg-bovg-T25608-Ab-2 | Anti-Bovine GPR40/FFAR1 monoclonal antibody | Bovine |
| GM-Tg-equg-T25608-Ab-1/ GM-Tg-equg-T25608-Ab-2 | Anti-Equine GPR40/FFAR1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T25608-Ab-1/ GM-Tg-hg-T25608-Ab-2; GM-Tg-rg-T25608-Ab-1/ GM-Tg-rg-T25608-Ab-2; GM-Tg-mg-T25608-Ab-1/ GM-Tg-mg-T25608-Ab-2; GM-Tg-cynog-T25608-Ab-1/ GM-Tg-cynog-T25608-Ab-2; GM-Tg-felg-T25608-Ab-1/ GM-Tg-felg-T25608-Ab-2; GM-Tg-cang-T25608-Ab-1/ GM-Tg-cang-T25608-Ab-2; GM-Tg-bovg-T25608-Ab-1/ GM-Tg-bovg-T25608-Ab-2; GM-Tg-equg-T25608-Ab-1/ GM-Tg-equg-T25608-Ab-2 |
| Products Name | Anti-GPR40/FFAR1 monoclonal antibody |
| Format | mab |
| Target Name | GPR40 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-GPR40 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species FFAR1/ GPR40/ FFA1R VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP003785 | human FFAR1 Lentivirus particle |
| ORF Viral Vector | pGMLP003785 | human FFAR1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm003400 | mouse Ffar1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003400 | mouse Ffar1 Lentivirus particle |
Target information
| Target ID | GM-T25608 |
| Target Name | GPR40 |
| Gene ID | 2864,233081,266607,708620,612661,101101019,618180,100059338 |
| Gene Symbol and Synonyms | FFA1R,FFAR1,GPCR40,GPR40 |
| Uniprot Accession | O14842,Q8K3T4 |
| Uniprot Entry Name | FFAR1_HUMAN,FFAR1_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000126266 |
| Target Classification | GPCR |
The target: GPR40, gene name: FFAR1, also named as FFA1R, GPCR40, GPR40. This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for medium and long chain free fatty acids and may be involved in the metabolic regulation of insulin secretion. Polymorphisms in this gene may be associated with type 2 diabetes. [provided by RefSeq, Apr 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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