Anti-FAF1 monoclonal antibody

Pre-made anti-FAF1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to FAF1/FAF1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T28093-Ab-1/ GM-Tg-hg-T28093-Ab-2Anti-Human FAF1 monoclonal antibodyHuman
GM-Tg-rg-T28093-Ab-1/ GM-Tg-rg-T28093-Ab-2Anti-Rat FAF1 monoclonal antibodyRat
GM-Tg-mg-T28093-Ab-1/ GM-Tg-mg-T28093-Ab-2Anti-Mouse FAF1 monoclonal antibodyMouse
GM-Tg-cynog-T28093-Ab-1/ GM-Tg-cynog-T28093-Ab-2Anti-Cynomolgus/ Rhesus macaque FAF1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T28093-Ab-1/ GM-Tg-felg-T28093-Ab-2Anti-Feline FAF1 monoclonal antibodyFeline
GM-Tg-cang-T28093-Ab-1/ GM-Tg-cang-T28093-Ab-2Anti-Canine FAF1 monoclonal antibodyCanine
GM-Tg-bovg-T28093-Ab-1/ GM-Tg-bovg-T28093-Ab-2Anti-Bovine FAF1 monoclonal antibodyBovine
GM-Tg-equg-T28093-Ab-1/ GM-Tg-equg-T28093-Ab-2Anti-Equine FAF1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T28093-Ab-1/ GM-Tg-hg-T28093-Ab-2; GM-Tg-rg-T28093-Ab-1/ GM-Tg-rg-T28093-Ab-2;
GM-Tg-mg-T28093-Ab-1/ GM-Tg-mg-T28093-Ab-2; GM-Tg-cynog-T28093-Ab-1/ GM-Tg-cynog-T28093-Ab-2;
GM-Tg-felg-T28093-Ab-1/ GM-Tg-felg-T28093-Ab-2; GM-Tg-cang-T28093-Ab-1/ GM-Tg-cang-T28093-Ab-2;
GM-Tg-bovg-T28093-Ab-1/ GM-Tg-bovg-T28093-Ab-2; GM-Tg-equg-T28093-Ab-1/ GM-Tg-equg-T28093-Ab-2
Products NameAnti-FAF1 monoclonal antibody
Formatmab
Target NameFAF1
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-FAF1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T28093-Ag-1Recombinant multi-species FAF1/ CGI-03/ HFAF1s protein


    Target information

    Target IDGM-T28093
    Target NameFAF1
    Gene ID11124,14084,140657,714405,608231,101091034,531770,100062977
    Gene Symbol and SynonymsCGI-03,Dffrx,FAF1,Fam,hFAF1,HFAF1s,UBXD12,UBXN3A
    Uniprot AccessionQ9UNN5,Q924K2
    Uniprot Entry NameFAF1_HUMAN,FAF1_RAT
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseOveractive bladder
    Gene EnsemblENSG00000185104
    Target ClassificationN/A

    The target: FAF1, gene name: FAF1, also named as CGI-03, HFAF1s, UBXD12, UBXN3A, hFAF1. Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.