Anti-FAF1 monoclonal antibody
Pre-made anti-FAF1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T28093-Ab-1/ GM-Tg-hg-T28093-Ab-2 | Anti-Human FAF1 monoclonal antibody | Human |
GM-Tg-rg-T28093-Ab-1/ GM-Tg-rg-T28093-Ab-2 | Anti-Rat FAF1 monoclonal antibody | Rat |
GM-Tg-mg-T28093-Ab-1/ GM-Tg-mg-T28093-Ab-2 | Anti-Mouse FAF1 monoclonal antibody | Mouse |
GM-Tg-cynog-T28093-Ab-1/ GM-Tg-cynog-T28093-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FAF1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T28093-Ab-1/ GM-Tg-felg-T28093-Ab-2 | Anti-Feline FAF1 monoclonal antibody | Feline |
GM-Tg-cang-T28093-Ab-1/ GM-Tg-cang-T28093-Ab-2 | Anti-Canine FAF1 monoclonal antibody | Canine |
GM-Tg-bovg-T28093-Ab-1/ GM-Tg-bovg-T28093-Ab-2 | Anti-Bovine FAF1 monoclonal antibody | Bovine |
GM-Tg-equg-T28093-Ab-1/ GM-Tg-equg-T28093-Ab-2 | Anti-Equine FAF1 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-T28093-Ab-1/ GM-Tg-hg-T28093-Ab-2; GM-Tg-rg-T28093-Ab-1/ GM-Tg-rg-T28093-Ab-2; GM-Tg-mg-T28093-Ab-1/ GM-Tg-mg-T28093-Ab-2; GM-Tg-cynog-T28093-Ab-1/ GM-Tg-cynog-T28093-Ab-2; GM-Tg-felg-T28093-Ab-1/ GM-Tg-felg-T28093-Ab-2; GM-Tg-cang-T28093-Ab-1/ GM-Tg-cang-T28093-Ab-2; GM-Tg-bovg-T28093-Ab-1/ GM-Tg-bovg-T28093-Ab-2; GM-Tg-equg-T28093-Ab-1/ GM-Tg-equg-T28093-Ab-2 |
Products Name | Anti-FAF1 monoclonal antibody |
Format | mab |
Target Name | FAF1 |
Protein Sub-location | Introcelluar Protein |
Category of antibody | Therapeutics Target antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-FAF1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-T28093-Ag-1 | Recombinant multi-species FAF1/ CGI-03/ HFAF1s protein |
Target information
Target ID | GM-T28093 |
Target Name | FAF1 |
Gene ID | 11124,14084,140657,714405,608231,101091034,531770,100062977 |
Gene Symbol and Synonyms | CGI-03,Dffrx,FAF1,Fam,hFAF1,HFAF1s,UBXD12,UBXN3A |
Uniprot Accession | Q9UNN5,Q924K2 |
Uniprot Entry Name | FAF1_HUMAN,FAF1_RAT |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Overactive bladder |
Gene Ensembl | ENSG00000185104 |
Target Classification | N/A |
The target: FAF1, gene name: FAF1, also named as CGI-03, HFAF1s, UBXD12, UBXN3A, hFAF1. Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The protein encoded by this gene binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin-like domain but not the FAS-binding domain. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.