Anti-EGFL6/ MAEG/ W80 functional antibody

Anti-EGFL6/ MAEG/ W80 functional antibody for cell culture, ELISA & in-vivo assay

Target products collectionGo to EGFL6/EGFL6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T28620-Ab-1/ GM-Tg-hg-T28620-Ab-2Anti-Human EGFL6 monoclonal antibodyHuman
GM-Tg-rg-T28620-Ab-1/ GM-Tg-rg-T28620-Ab-2Anti-Rat EGFL6 monoclonal antibodyRat
GM-Tg-mg-T28620-Ab-1/ GM-Tg-mg-T28620-Ab-2Anti-Mouse EGFL6 monoclonal antibodyMouse
GM-Tg-cynog-T28620-Ab-1/ GM-Tg-cynog-T28620-Ab-2Anti-Cynomolgus/ Rhesus macaque EGFL6 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T28620-Ab-1/ GM-Tg-felg-T28620-Ab-2Anti-Feline EGFL6 monoclonal antibodyFeline
GM-Tg-cang-T28620-Ab-1/ GM-Tg-cang-T28620-Ab-2Anti-Canine EGFL6 monoclonal antibodyCanine
GM-Tg-bovg-T28620-Ab-1/ GM-Tg-bovg-T28620-Ab-2Anti-Bovine EGFL6 monoclonal antibodyBovine
GM-Tg-equg-T28620-Ab-1/ GM-Tg-equg-T28620-Ab-2Anti-Equine EGFL6 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T28620-Ab-1/ GM-Tg-hg-T28620-Ab-2; GM-Tg-rg-T28620-Ab-1/ GM-Tg-rg-T28620-Ab-2;
GM-Tg-mg-T28620-Ab-1/ GM-Tg-mg-T28620-Ab-2; GM-Tg-cynog-T28620-Ab-1/ GM-Tg-cynog-T28620-Ab-2;
GM-Tg-felg-T28620-Ab-1/ GM-Tg-felg-T28620-Ab-2; GM-Tg-cang-T28620-Ab-1/ GM-Tg-cang-T28620-Ab-2;
GM-Tg-bovg-T28620-Ab-1/ GM-Tg-bovg-T28620-Ab-2; GM-Tg-equg-T28620-Ab-1/ GM-Tg-equg-T28620-Ab-2
Products NameAnti-EGFL6 monoclonal antibody
Formatmab
Target NameEGFL6
Protein Sub-locationSecreted Protein/Potential Cytokines
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-EGFL6 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T28620-Ag-1Recombinant multi-species EGFL6/ MAEG/ W80 protein
    CytokineGM-Tg-g-T28620-Ag-1EGF-like-domain, multiple 6 (EGFL6) protein
    ORF Viral VectorpGMLPm003488mouse Egfl6 Lentivirus plasmid
    ORF Viral VectorvGMLPm003488mouse Egfl6 Lentivirus particle


    Target information

    Target IDGM-T28620
    Target NameEGFL6
    Gene ID25975,54156,317470,711280,491745,101092495,100054915
    Gene Symbol and SynonymsEGFL6,MAEG,W80
    Uniprot AccessionQ8IUX8
    Uniprot Entry NameEGFL6_HUMAN
    Protein Sub-locationSecreted Protein/Potential Cytokines
    CategoryTherapeutics Target, Cytokine Target
    DiseaseOvary Cancer
    Gene EnsemblENSG00000198759
    Target ClassificationN/A

    The target: EGFL6, gene name: EGFL6, also named as MAEG, W80. This gene encodes a member of the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. The gene product contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is believed to have an adhesive function. This gene is expressed early during development, and its expression has been detected in lung and meningioma tumors. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.