Anti-TUBB2 monoclonal antibody

Pre-made anti-TUBB2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to TUBB2/TUBB2A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T28661-Ab-1/ GM-Tg-hg-T28661-Ab-2Anti-Human TUBB2/TUBB2A monoclonal antibodyHuman
GM-Tg-rg-T28661-Ab-1/ GM-Tg-rg-T28661-Ab-2Anti-Rat TUBB2/TUBB2A monoclonal antibodyRat
GM-Tg-mg-T28661-Ab-1/ GM-Tg-mg-T28661-Ab-2Anti-Mouse TUBB2/TUBB2A monoclonal antibodyMouse
GM-Tg-cynog-T28661-Ab-1/ GM-Tg-cynog-T28661-Ab-2Anti-Cynomolgus/ Rhesus macaque TUBB2/TUBB2A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T28661-Ab-1/ GM-Tg-felg-T28661-Ab-2Anti-Feline TUBB2/TUBB2A monoclonal antibodyFeline
GM-Tg-cang-T28661-Ab-1/ GM-Tg-cang-T28661-Ab-2Anti-Canine TUBB2/TUBB2A monoclonal antibodyCanine
GM-Tg-bovg-T28661-Ab-1/ GM-Tg-bovg-T28661-Ab-2Anti-Bovine TUBB2/TUBB2A monoclonal antibodyBovine
GM-Tg-equg-T28661-Ab-1/ GM-Tg-equg-T28661-Ab-2Anti-Equine TUBB2/TUBB2A monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T28661-Ab-1/ GM-Tg-hg-T28661-Ab-2; GM-Tg-rg-T28661-Ab-1/ GM-Tg-rg-T28661-Ab-2;
GM-Tg-mg-T28661-Ab-1/ GM-Tg-mg-T28661-Ab-2; GM-Tg-cynog-T28661-Ab-1/ GM-Tg-cynog-T28661-Ab-2;
GM-Tg-felg-T28661-Ab-1/ GM-Tg-felg-T28661-Ab-2; GM-Tg-cang-T28661-Ab-1/ GM-Tg-cang-T28661-Ab-2;
GM-Tg-bovg-T28661-Ab-1/ GM-Tg-bovg-T28661-Ab-2; GM-Tg-equg-T28661-Ab-1/ GM-Tg-equg-T28661-Ab-2
Products NameAnti-TUBB2/TUBB2A monoclonal antibody
Formatmab
Target NameTUBB2
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-TUBB2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T28661-Ag-1Recombinant multi-species TBB2A/ TUBB2/ TUBB2A protein
    ORF Viral VectorvGMLP000050human TUBB2A Lentivirus particle
    ORF Viral VectorpGMLP000050human TUBB2A Lentivirus plasmid
    ORF Viral VectorpGMLPm003969mouse Tubb2a Lentivirus plasmid
    ORF Viral VectorvGMLPm003969mouse Tubb2a Lentivirus particle


    Target information

    Target IDGM-T28661
    Target NameTUBB2
    Gene ID7280,22151,478701,109499596,100295973,100629875
    Gene Symbol and SynonymsCDCBM5,M(beta)2,TUBB,TUBB2,TUBB2A
    Uniprot AccessionQ13885
    Uniprot Entry NameTBB2A_HUMAN
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000137267
    Target ClassificationN/A

    The target: TUBB2, gene name: TUBB2A, also named as CDCBM5, TUBB, TUBB2. Microtubules, key participants in processes such as mitosis and intracellular transport, are composed of heterodimers of alpha- and beta-tubulins. The protein encoded by this gene is a beta-tubulin. Defects in this gene are associated with complex cortical dysplasia with other brain malformations-5. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2015].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.