Anti-FGF14 monoclonal antibody

Pre-made anti-FGF14 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to FGF14/FGF14 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T29481-Ab-1/ GM-Tg-hg-T29481-Ab-2Anti-Human FGF14 monoclonal antibodyHuman
GM-Tg-rg-T29481-Ab-1/ GM-Tg-rg-T29481-Ab-2Anti-Rat FGF14 monoclonal antibodyRat
GM-Tg-mg-T29481-Ab-1/ GM-Tg-mg-T29481-Ab-2Anti-Mouse FGF14 monoclonal antibodyMouse
GM-Tg-cynog-T29481-Ab-1/ GM-Tg-cynog-T29481-Ab-2Anti-Cynomolgus/ Rhesus macaque FGF14 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T29481-Ab-1/ GM-Tg-felg-T29481-Ab-2Anti-Feline FGF14 monoclonal antibodyFeline
GM-Tg-cang-T29481-Ab-1/ GM-Tg-cang-T29481-Ab-2Anti-Canine FGF14 monoclonal antibodyCanine
GM-Tg-bovg-T29481-Ab-1/ GM-Tg-bovg-T29481-Ab-2Anti-Bovine FGF14 monoclonal antibodyBovine
GM-Tg-equg-T29481-Ab-1/ GM-Tg-equg-T29481-Ab-2Anti-Equine FGF14 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T29481-Ab-1/ GM-Tg-hg-T29481-Ab-2; GM-Tg-rg-T29481-Ab-1/ GM-Tg-rg-T29481-Ab-2;
GM-Tg-mg-T29481-Ab-1/ GM-Tg-mg-T29481-Ab-2; GM-Tg-cynog-T29481-Ab-1/ GM-Tg-cynog-T29481-Ab-2;
GM-Tg-felg-T29481-Ab-1/ GM-Tg-felg-T29481-Ab-2; GM-Tg-cang-T29481-Ab-1/ GM-Tg-cang-T29481-Ab-2;
GM-Tg-bovg-T29481-Ab-1/ GM-Tg-bovg-T29481-Ab-2; GM-Tg-equg-T29481-Ab-1/ GM-Tg-equg-T29481-Ab-2
Products NameAnti-FGF14 monoclonal antibody
Formatmab
Target NameFGF14
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody, Cytokine antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-FGF14 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T29481-Ag-1Recombinant multi-species FGF14/ FGF-14/ FHF-4 protein
    CytokineGM-Tg-g-T29481-Ag-1fibroblast growth factor 14 (FGF14) protein
    ORF Viral VectorpGMLP000931human FGF14 Lentivirus plasmid
    ORF Viral VectorvGMLP000931human FGF14 Lentivirus particle
    ORF Viral VectorpGMLPm001132mouse Fgf14 Lentivirus plasmid
    ORF Viral VectorvGMLPm001132mouse Fgf14 Lentivirus particle


    Target information

    Target IDGM-T29481
    Target NameFGF14
    Gene ID2259,14169,63851,701077,485537,101082119,615488,100050897
    Gene Symbol and SynonymsFGF-14,FGF14,Fgf1b,FHF-4,FHF4,mFHF-4(1B),NYS4,SCA27,SCA27A,SCA27B,Tg(tetO-MAPT*P301L)4510Kha
    Uniprot AccessionQ92915,Q8R5L7
    Uniprot Entry NameFGF14_HUMAN,FGF14_RAT
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target, Cytokine Target
    DiseaseN/A
    Gene EnsemblENSG00000102466
    Target ClassificationN/A

    The target: FGF14, gene name: FGF14, also named as FGF-14, FHF-4, FHF4, SCA27. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.