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Anti-SO2B1/ SLCO2B1/ OATP-B monoclonal antibody
Anti-SO2B1/ SLCO2B1/ OATP-B antibody for FACS & in-vivo assay
Go to SLCO2B1/SLCO2B1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T34064-Ab-1/ GM-Tg-hg-T34064-Ab-2 | Anti-Human SLCO2B1 monoclonal antibody | Human |
| GM-Tg-rg-T34064-Ab-1/ GM-Tg-rg-T34064-Ab-2 | Anti-Rat SLCO2B1 monoclonal antibody | Rat |
| GM-Tg-mg-T34064-Ab-1/ GM-Tg-mg-T34064-Ab-2 | Anti-Mouse SLCO2B1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T34064-Ab-1/ GM-Tg-cynog-T34064-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLCO2B1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T34064-Ab-1/ GM-Tg-felg-T34064-Ab-2 | Anti-Feline SLCO2B1 monoclonal antibody | Feline |
| GM-Tg-cang-T34064-Ab-1/ GM-Tg-cang-T34064-Ab-2 | Anti-Canine SLCO2B1 monoclonal antibody | Canine |
| GM-Tg-bovg-T34064-Ab-1/ GM-Tg-bovg-T34064-Ab-2 | Anti-Bovine SLCO2B1 monoclonal antibody | Bovine |
| GM-Tg-equg-T34064-Ab-1/ GM-Tg-equg-T34064-Ab-2 | Anti-Equine SLCO2B1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T34064-Ab-1/ GM-Tg-hg-T34064-Ab-2; GM-Tg-rg-T34064-Ab-1/ GM-Tg-rg-T34064-Ab-2; GM-Tg-mg-T34064-Ab-1/ GM-Tg-mg-T34064-Ab-2; GM-Tg-cynog-T34064-Ab-1/ GM-Tg-cynog-T34064-Ab-2; GM-Tg-felg-T34064-Ab-1/ GM-Tg-felg-T34064-Ab-2; GM-Tg-cang-T34064-Ab-1/ GM-Tg-cang-T34064-Ab-2; GM-Tg-bovg-T34064-Ab-1/ GM-Tg-bovg-T34064-Ab-2; GM-Tg-equg-T34064-Ab-1/ GM-Tg-equg-T34064-Ab-2 |
| Products Name | Anti-SLCO2B1 monoclonal antibody |
| Format | mab |
| Target Name | SLCO2B1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SLCO2B1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species SO2B1/ SLCO2B1/ OATP-B VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLV000174 | human SLCO2B1 Lentivirus particle |
| ORF Viral Vector | pGMLV000174 | human SLCO2B1 Lentivirus plasmid |
Target information
| Target ID | GM-T34064 |
| Target Name | SLCO2B1 |
| Gene ID | 11309,101488,140860,694829,485192,101101333,317704,100009692 |
| Gene Symbol and Synonyms | moat1,OATP-B,OATP2B1,OATPB,SLC21A9,SLCO2B1 |
| Uniprot Accession | O94956,Q9JHI3 |
| Uniprot Entry Name | SO2B1_HUMAN,SO2B1_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000137491 |
| Target Classification | N/A |
The target: SLCO2B1, gene name: SLCO2B1, also named as OATP-B, OATP2B1, OATPB, SLC21A9. This locus encodes a member of the organic anion-transporting polypeptide family of membrane proteins. The protein encoded by this locus may function in regulation of placental uptake of sulfated steroids. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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