Anti-SO4C1/ SLCO4C1/ OATP-H monoclonal antibody

Anti-SO4C1/ SLCO4C1/ OATP-H antibody for FACS & in-vivo assay

Target products collectionGo to SLCO4C1/SLCO4C1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T36053-Ab-1/ GM-Tg-hg-T36053-Ab-2Anti-Human SLCO4C1 monoclonal antibodyHuman
GM-Tg-rg-T36053-Ab-1/ GM-Tg-rg-T36053-Ab-2Anti-Rat SLCO4C1 monoclonal antibodyRat
GM-Tg-mg-T36053-Ab-1/ GM-Tg-mg-T36053-Ab-2Anti-Mouse SLCO4C1 monoclonal antibodyMouse
GM-Tg-cynog-T36053-Ab-1/ GM-Tg-cynog-T36053-Ab-2Anti-Cynomolgus/ Rhesus macaque SLCO4C1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T36053-Ab-1/ GM-Tg-felg-T36053-Ab-2Anti-Feline SLCO4C1 monoclonal antibodyFeline
GM-Tg-cang-T36053-Ab-1/ GM-Tg-cang-T36053-Ab-2Anti-Canine SLCO4C1 monoclonal antibodyCanine
GM-Tg-bovg-T36053-Ab-1/ GM-Tg-bovg-T36053-Ab-2Anti-Bovine SLCO4C1 monoclonal antibodyBovine
GM-Tg-equg-T36053-Ab-1/ GM-Tg-equg-T36053-Ab-2Anti-Equine SLCO4C1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T36053-Ab-1/ GM-Tg-hg-T36053-Ab-2; GM-Tg-rg-T36053-Ab-1/ GM-Tg-rg-T36053-Ab-2;
GM-Tg-mg-T36053-Ab-1/ GM-Tg-mg-T36053-Ab-2; GM-Tg-cynog-T36053-Ab-1/ GM-Tg-cynog-T36053-Ab-2;
GM-Tg-felg-T36053-Ab-1/ GM-Tg-felg-T36053-Ab-2; GM-Tg-cang-T36053-Ab-1/ GM-Tg-cang-T36053-Ab-2;
GM-Tg-bovg-T36053-Ab-1/ GM-Tg-bovg-T36053-Ab-2; GM-Tg-equg-T36053-Ab-1/ GM-Tg-equg-T36053-Ab-2
Products NameAnti-SLCO4C1 monoclonal antibody
Formatmab
Target NameSLCO4C1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLCO4C1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SO4C1/ SLCO4C1/ OATP-H VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-T36053
    Target NameSLCO4C1
    Gene ID353189,227394,432363,702748,100686528,101090738,497621,100073212
    Gene Symbol and Synonyms9530051F04,C330017E21Rik,OATP-H,OATP-M1,oatp-R,OATP4C1,OATPX,PRO2176,SLC21A20,SLCO4C1
    Uniprot AccessionQ6ZQN7,Q71MB6
    Uniprot Entry NameSO4C1_HUMAN,SO4C1_RAT
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000173930
    Target ClassificationN/A

    The target: SLCO4C1, gene name: SLCO4C1, also named as OATP-H, OATP-M1, OATP4C1, OATPX, PRO2176, SLC21A20. SLCO4C1 belongs to the organic anion transporter (OATP) family. OATPs are involved in the membrane transport of bile acids, conjugated steroids, thyroid hormone, eicosanoids, peptides, and numerous drugs in many tissues (Mikkaichi et al., 2004 [PubMed 14993604]).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.