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Anti-ANXA1/ PA2IP/ ANX1 monoclonal antibody
Anti-ANXA1/ PA2IP/ ANX1 antibody for FACS & in-vivo assay
Go to PA2IP/ANXA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T38161-Ab-1/ GM-Tg-hg-T38161-Ab-2 | Anti-Human PA2IP/ANXA1 monoclonal antibody | Human |
| GM-Tg-rg-T38161-Ab-1/ GM-Tg-rg-T38161-Ab-2 | Anti-Rat PA2IP/ANXA1 monoclonal antibody | Rat |
| GM-Tg-mg-T38161-Ab-1/ GM-Tg-mg-T38161-Ab-2 | Anti-Mouse PA2IP/ANXA1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T38161-Ab-1/ GM-Tg-cynog-T38161-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PA2IP/ANXA1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T38161-Ab-1/ GM-Tg-felg-T38161-Ab-2 | Anti-Feline PA2IP/ANXA1 monoclonal antibody | Feline |
| GM-Tg-cang-T38161-Ab-1/ GM-Tg-cang-T38161-Ab-2 | Anti-Canine PA2IP/ANXA1 monoclonal antibody | Canine |
| GM-Tg-bovg-T38161-Ab-1/ GM-Tg-bovg-T38161-Ab-2 | Anti-Bovine PA2IP/ANXA1 monoclonal antibody | Bovine |
| GM-Tg-equg-T38161-Ab-1/ GM-Tg-equg-T38161-Ab-2 | Anti-Equine PA2IP/ANXA1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T38161-Ab-1/ GM-Tg-hg-T38161-Ab-2; GM-Tg-rg-T38161-Ab-1/ GM-Tg-rg-T38161-Ab-2; GM-Tg-mg-T38161-Ab-1/ GM-Tg-mg-T38161-Ab-2; GM-Tg-cynog-T38161-Ab-1/ GM-Tg-cynog-T38161-Ab-2; GM-Tg-felg-T38161-Ab-1/ GM-Tg-felg-T38161-Ab-2; GM-Tg-cang-T38161-Ab-1/ GM-Tg-cang-T38161-Ab-2; GM-Tg-bovg-T38161-Ab-1/ GM-Tg-bovg-T38161-Ab-2; GM-Tg-equg-T38161-Ab-1/ GM-Tg-equg-T38161-Ab-2 |
| Products Name | Anti-PA2IP/ANXA1 monoclonal antibody |
| Format | mab |
| Target Name | PA2IP |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PA2IP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species ANXA1/ PA2IP/ ANX1 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMAP000175 | Human ANXA1 Adenovirus particle |
| ORF Viral Vector | pGMAD000020 | human ANXA1 Adenovirus plasmid |
| ORF Viral Vector | pGMAD000418 | human ANXA1 Adenovirus plasmid |
| ORF Viral Vector | vGMAD000418 | human ANXA1 Adenovirus particle |
| ORF Viral Vector | vGMLV000465 | human ANXA1 Lentivirus particle |
| ORF Viral Vector | pGMLV000465 | human ANXA1 Lentivirus plasmid |
| ORF Viral Vector | vGMAD000020 | human ANXA1 Adenovirus particle |
| ORF Viral Vector | pGMAP000175 | Human ANXA1 Adenovirus plasmid |
| ORF Viral Vector | pGMLV000146 | mouse Anxa1 Lentivirus plasmid |
| ORF Viral Vector | pGMLV000523 | house mouse Anxa1 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000146 | mouse Anxa1 Lentivirus particle |
| ORF Viral Vector | vGMLV000523 | house mouse Anxa1 Lentivirus particle |
Target information
| Target ID | GM-T38161 |
| Target Name | PA2IP |
| Gene ID | 301,16952,25380,702946,476322,493875,327662,100033940 |
| Gene Symbol and Synonyms | Anx-1,Anx-A1,ANX1,ANXA1,C430014K04Rik,Lpc-1,LPC1,p35 |
| Uniprot Accession | P04083,P07150,P46193,Q8HZM6 |
| Uniprot Entry Name | ANXA1_HUMAN,ANXA1_RAT,ANXA1_BOVIN,ANXA1_HORSE |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | Lung Cancer, Glomerulonephritis |
| Gene Ensembl | ENSG00000135046 |
| Target Classification | N/A |
The target: PA2IP, gene name: ANXA1, also named as ANX1, LPC1. This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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