Anti-TIPARP monoclonal antibody

Pre-made anti-TIPARP monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to TIPARP/TIPARP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T38201-Ab-1/ GM-Tg-hg-T38201-Ab-2Anti-Human TIPARP monoclonal antibodyHuman
GM-Tg-rg-T38201-Ab-1/ GM-Tg-rg-T38201-Ab-2Anti-Rat TIPARP monoclonal antibodyRat
GM-Tg-mg-T38201-Ab-1/ GM-Tg-mg-T38201-Ab-2Anti-Mouse TIPARP monoclonal antibodyMouse
GM-Tg-cynog-T38201-Ab-1/ GM-Tg-cynog-T38201-Ab-2Anti-Cynomolgus/ Rhesus macaque TIPARP monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T38201-Ab-1/ GM-Tg-felg-T38201-Ab-2Anti-Feline TIPARP monoclonal antibodyFeline
GM-Tg-cang-T38201-Ab-1/ GM-Tg-cang-T38201-Ab-2Anti-Canine TIPARP monoclonal antibodyCanine
GM-Tg-bovg-T38201-Ab-1/ GM-Tg-bovg-T38201-Ab-2Anti-Bovine TIPARP monoclonal antibodyBovine
GM-Tg-equg-T38201-Ab-1/ GM-Tg-equg-T38201-Ab-2Anti-Equine TIPARP monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T38201-Ab-1/ GM-Tg-hg-T38201-Ab-2; GM-Tg-rg-T38201-Ab-1/ GM-Tg-rg-T38201-Ab-2;
GM-Tg-mg-T38201-Ab-1/ GM-Tg-mg-T38201-Ab-2; GM-Tg-cynog-T38201-Ab-1/ GM-Tg-cynog-T38201-Ab-2;
GM-Tg-felg-T38201-Ab-1/ GM-Tg-felg-T38201-Ab-2; GM-Tg-cang-T38201-Ab-1/ GM-Tg-cang-T38201-Ab-2;
GM-Tg-bovg-T38201-Ab-1/ GM-Tg-bovg-T38201-Ab-2; GM-Tg-equg-T38201-Ab-1/ GM-Tg-equg-T38201-Ab-2
Products NameAnti-TIPARP monoclonal antibody
Formatmab
Target NameTIPARP
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-TIPARP monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T38201-Ag-1Recombinant multi-species PARPT/ TIPARP/ ARTD14 protein
    ORF Viral VectorvGMLV000656human TIPARP Lentivirus particle
    ORF Viral VectorpGMLV000656human TIPARP Lentivirus plasmid


    Target information

    Target IDGM-T38201
    Target NameTIPARP
    Gene ID25976,99929,310467,706180,485728,101085655,540975,100050358
    Gene Symbol and SynonymsARTD14,PARP7,pART14,RM1,TIPARP
    Uniprot AccessionQ7Z3E1
    Uniprot Entry NamePARPT_HUMAN
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000163659
    Target ClassificationN/A

    The target: TIPARP, gene name: TIPARP, also named as ARTD14, PARP7, pART14. This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.