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Anti-TNKS-1 monoclonal antibody
Pre-made anti-TNKS-1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to TNKS-1/TNKS products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T39231-Ab-1/ GM-Tg-hg-T39231-Ab-2 | Anti-Human TNKS-1/TNKS monoclonal antibody | Human |
| GM-Tg-rg-T39231-Ab-1/ GM-Tg-rg-T39231-Ab-2 | Anti-Rat TNKS-1/TNKS monoclonal antibody | Rat |
| GM-Tg-mg-T39231-Ab-1/ GM-Tg-mg-T39231-Ab-2 | Anti-Mouse TNKS-1/TNKS monoclonal antibody | Mouse |
| GM-Tg-cynog-T39231-Ab-1/ GM-Tg-cynog-T39231-Ab-2 | Anti-Cynomolgus/ Rhesus macaque TNKS-1/TNKS monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T39231-Ab-1/ GM-Tg-felg-T39231-Ab-2 | Anti-Feline TNKS-1/TNKS monoclonal antibody | Feline |
| GM-Tg-cang-T39231-Ab-1/ GM-Tg-cang-T39231-Ab-2 | Anti-Canine TNKS-1/TNKS monoclonal antibody | Canine |
| GM-Tg-bovg-T39231-Ab-1/ GM-Tg-bovg-T39231-Ab-2 | Anti-Bovine TNKS-1/TNKS monoclonal antibody | Bovine |
| GM-Tg-equg-T39231-Ab-1/ GM-Tg-equg-T39231-Ab-2 | Anti-Equine TNKS-1/TNKS monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T39231-Ab-1/ GM-Tg-hg-T39231-Ab-2; GM-Tg-rg-T39231-Ab-1/ GM-Tg-rg-T39231-Ab-2; GM-Tg-mg-T39231-Ab-1/ GM-Tg-mg-T39231-Ab-2; GM-Tg-cynog-T39231-Ab-1/ GM-Tg-cynog-T39231-Ab-2; GM-Tg-felg-T39231-Ab-1/ GM-Tg-felg-T39231-Ab-2; GM-Tg-cang-T39231-Ab-1/ GM-Tg-cang-T39231-Ab-2; GM-Tg-bovg-T39231-Ab-1/ GM-Tg-bovg-T39231-Ab-2; GM-Tg-equg-T39231-Ab-1/ GM-Tg-equg-T39231-Ab-2 |
| Products Name | Anti-TNKS-1/TNKS monoclonal antibody |
| Format | mab |
| Target Name | TNKS-1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-TNKS-1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T39231-Ag-1 | Recombinant multi-species TNKS1/ TNKS-1/ TNKS protein |
| ORF Viral Vector | pGMAD000159 | human TNKS Adenovirus plasmid |
| ORF Viral Vector | vGMAD000159 | human TNKS Adenovirus particle |
Target information
| Target ID | GM-T39231 |
| Target Name | TNKS-1 |
| Gene ID | 8658,21951,290794,699004,475603,101092933,535030,100058499 |
| Gene Symbol and Synonyms | 4930554K12Rik,ARTD5,D130072O21Rik,mTNKS1,PARP-5a,PARP5A,PARPL,pART5,TANK1,TIN1,TINF1,TNKS,TNKS1 |
| Uniprot Accession | O95271 |
| Uniprot Entry Name | TNKS1_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000173273 |
| Target Classification | N/A |
The target: TNKS-1, gene name: TNKS, also named as ARTD5, PARP-5a, PARP5A, PARPL, TIN1, TINF11, pART5, TNKS. Enables histone binding activity; pentosyltransferase activity; and zinc ion binding activity. Involved in several processes, including negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric; protein ADP-ribosylation; and regulation of nucleobase-containing compound metabolic process. Acts upstream of or within peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; and protein ADP-ribosylation. Located in several cellular components, including chromosome, telomeric region; mitotic spindle pole; and nucleus. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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