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Anti-RPS6KB2 monoclonal antibody
Pre-made anti-RPS6KB2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to RPS6KB2/RPS6KB2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T42760-Ab-1/ GM-Tg-hg-T42760-Ab-2 | Anti-Human RPS6KB2 monoclonal antibody | Human |
| GM-Tg-rg-T42760-Ab-1/ GM-Tg-rg-T42760-Ab-2 | Anti-Rat RPS6KB2 monoclonal antibody | Rat |
| GM-Tg-mg-T42760-Ab-1/ GM-Tg-mg-T42760-Ab-2 | Anti-Mouse RPS6KB2 monoclonal antibody | Mouse |
| GM-Tg-cynog-T42760-Ab-1/ GM-Tg-cynog-T42760-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RPS6KB2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T42760-Ab-1/ GM-Tg-felg-T42760-Ab-2 | Anti-Feline RPS6KB2 monoclonal antibody | Feline |
| GM-Tg-cang-T42760-Ab-1/ GM-Tg-cang-T42760-Ab-2 | Anti-Canine RPS6KB2 monoclonal antibody | Canine |
| GM-Tg-bovg-T42760-Ab-1/ GM-Tg-bovg-T42760-Ab-2 | Anti-Bovine RPS6KB2 monoclonal antibody | Bovine |
| GM-Tg-equg-T42760-Ab-1/ GM-Tg-equg-T42760-Ab-2 | Anti-Equine RPS6KB2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T42760-Ab-1/ GM-Tg-hg-T42760-Ab-2; GM-Tg-rg-T42760-Ab-1/ GM-Tg-rg-T42760-Ab-2; GM-Tg-mg-T42760-Ab-1/ GM-Tg-mg-T42760-Ab-2; GM-Tg-cynog-T42760-Ab-1/ GM-Tg-cynog-T42760-Ab-2; GM-Tg-felg-T42760-Ab-1/ GM-Tg-felg-T42760-Ab-2; GM-Tg-cang-T42760-Ab-1/ GM-Tg-cang-T42760-Ab-2; GM-Tg-bovg-T42760-Ab-1/ GM-Tg-bovg-T42760-Ab-2; GM-Tg-equg-T42760-Ab-1/ GM-Tg-equg-T42760-Ab-2 |
| Products Name | Anti-RPS6KB2 monoclonal antibody |
| Format | mab |
| Target Name | RPS6KB2 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-RPS6KB2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T42760-Ag-1 | Recombinant multi-species KS6B2/ RPS6KB2/ KLS protein |
Target information
| Target ID | GM-T42760 |
| Target Name | RPS6KB2 |
| Gene ID | 6199,58988,361696,721731,610499,101091812,506083,100053005 |
| Gene Symbol and Synonyms | KLS,p70(S6K)-beta,P70-beta,P70-beta-1,P70-beta-2,p70S6Kb,RPS6KB2,S6K-beta-2,S6K-beta2,S6K2,S6KB,S6Kbeta,S6KI(2),SRK,STK14B |
| Uniprot Accession | Q9UBS0 |
| Uniprot Entry Name | KS6B2_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000175634 |
| Target Classification | N/A |
The target: RPS6KB2, gene name: RPS6KB2, also named as KLS, P70-beta, P70-beta-1, P70-beta-2, S6K-beta2, S6K2, S6KB, S6KI(2), S6Kbeta, SRK, STK14B, p70(S6K)-beta, p70S6Kb. This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [provided by RefSeq, Jan 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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