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Anti-FGF21 functional antibody
Anti-FGF21 functional antibody for cell culture, ELISA & in-vivo assay
Go to FGF21/FGF21 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T42928-Ab-1/ GM-Tg-hg-T42928-Ab-2 | Anti-Human FGF21 monoclonal antibody | Human |
| GM-Tg-rg-T42928-Ab-1/ GM-Tg-rg-T42928-Ab-2 | Anti-Rat FGF21 monoclonal antibody | Rat |
| GM-Tg-mg-T42928-Ab-1/ GM-Tg-mg-T42928-Ab-2 | Anti-Mouse FGF21 monoclonal antibody | Mouse |
| GM-Tg-cynog-T42928-Ab-1/ GM-Tg-cynog-T42928-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FGF21 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T42928-Ab-1/ GM-Tg-felg-T42928-Ab-2 | Anti-Feline FGF21 monoclonal antibody | Feline |
| GM-Tg-cang-T42928-Ab-1/ GM-Tg-cang-T42928-Ab-2 | Anti-Canine FGF21 monoclonal antibody | Canine |
| GM-Tg-bovg-T42928-Ab-1/ GM-Tg-bovg-T42928-Ab-2 | Anti-Bovine FGF21 monoclonal antibody | Bovine |
| GM-Tg-equg-T42928-Ab-1/ GM-Tg-equg-T42928-Ab-2 | Anti-Equine FGF21 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T42928-Ab-1/ GM-Tg-hg-T42928-Ab-2; GM-Tg-rg-T42928-Ab-1/ GM-Tg-rg-T42928-Ab-2; GM-Tg-mg-T42928-Ab-1/ GM-Tg-mg-T42928-Ab-2; GM-Tg-cynog-T42928-Ab-1/ GM-Tg-cynog-T42928-Ab-2; GM-Tg-felg-T42928-Ab-1/ GM-Tg-felg-T42928-Ab-2; GM-Tg-cang-T42928-Ab-1/ GM-Tg-cang-T42928-Ab-2; GM-Tg-bovg-T42928-Ab-1/ GM-Tg-bovg-T42928-Ab-2; GM-Tg-equg-T42928-Ab-1/ GM-Tg-equg-T42928-Ab-2 |
| Products Name | Anti-FGF21 monoclonal antibody |
| Format | mab |
| Target Name | FGF21 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-FGF21 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T42928-Ag-1 | Recombinant multi-species FGF21 protein |
| Cytokine | GM-Tg-g-T42928-Ag-1 | fibroblast growth factor 21 (FGF21) protein |
| ORF Viral Vector | vGMLP003451 | human FGF21 Lentivirus particle |
| ORF Viral Vector | pGMLP003451 | human FGF21 Lentivirus plasmid |
| ORF Viral Vector | pGMAAV000245 | human FGF21 AAV plasmid |
| ORF Viral Vector | vGMAAV000245 | human FGF21 AAV particle |
| ORF Viral Vector | pGMLV000086 | mouse Fgf21 Lentivirus plasmid |
| ORF Viral Vector | pGMLV000538 | house mouse Fgf21 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000086 | mouse Fgf21 Lentivirus particle |
| ORF Viral Vector | vGMLV000538 | house mouse Fgf21 Lentivirus particle |
Target information
| Target ID | GM-T42928 |
| Target Name | FGF21 |
| Gene ID | 26291,56636,170580,718288,484395,101080595,785576,100054542 |
| Gene Symbol and Synonyms | FGF21,Fgf8c |
| Uniprot Accession | Q9NSA1 |
| Uniprot Entry Name | FGF21_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000105550 |
| Target Classification | N/A |
The target: FGF21, gene name: FGF21, also named as . Theis gene encodes a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. This protein is a secreted endocrine factor that functions as a major metabolic regulator. The encoded protein stimulates the uptake of glucose in adipose tissue. [provided by RefSeq, Mar 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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