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Anti-RORA monoclonal antibody
Pre-made anti-RORA monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to RORA/RORA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T43206-Ab-1/ GM-Tg-hg-T43206-Ab-2 | Anti-Human RORA monoclonal antibody | Human |
| GM-Tg-rg-T43206-Ab-1/ GM-Tg-rg-T43206-Ab-2 | Anti-Rat RORA monoclonal antibody | Rat |
| GM-Tg-mg-T43206-Ab-1/ GM-Tg-mg-T43206-Ab-2 | Anti-Mouse RORA monoclonal antibody | Mouse |
| GM-Tg-cynog-T43206-Ab-1/ GM-Tg-cynog-T43206-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RORA monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T43206-Ab-1/ GM-Tg-felg-T43206-Ab-2 | Anti-Feline RORA monoclonal antibody | Feline |
| GM-Tg-cang-T43206-Ab-1/ GM-Tg-cang-T43206-Ab-2 | Anti-Canine RORA monoclonal antibody | Canine |
| GM-Tg-bovg-T43206-Ab-1/ GM-Tg-bovg-T43206-Ab-2 | Anti-Bovine RORA monoclonal antibody | Bovine |
| GM-Tg-equg-T43206-Ab-1/ GM-Tg-equg-T43206-Ab-2 | Anti-Equine RORA monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T43206-Ab-1/ GM-Tg-hg-T43206-Ab-2; GM-Tg-rg-T43206-Ab-1/ GM-Tg-rg-T43206-Ab-2; GM-Tg-mg-T43206-Ab-1/ GM-Tg-mg-T43206-Ab-2; GM-Tg-cynog-T43206-Ab-1/ GM-Tg-cynog-T43206-Ab-2; GM-Tg-felg-T43206-Ab-1/ GM-Tg-felg-T43206-Ab-2; GM-Tg-cang-T43206-Ab-1/ GM-Tg-cang-T43206-Ab-2; GM-Tg-bovg-T43206-Ab-1/ GM-Tg-bovg-T43206-Ab-2; GM-Tg-equg-T43206-Ab-1/ GM-Tg-equg-T43206-Ab-2 |
| Products Name | Anti-RORA monoclonal antibody |
| Format | mab |
| Target Name | RORA |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-RORA monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T43206-Ag-1 | Recombinant multi-species RORA/ IDDECA/ NR1F1 protein |
| ORF Viral Vector | pGMLV000037 | human RORA Lentivirus plasmid |
| ORF Viral Vector | vGMLV000037 | human RORA Lentivirus particle |
| ORF Viral Vector | pGMAD000633 | house mouse Rora Adenovirus plasmid |
| ORF Viral Vector | pGMLPm001751 | mouse Rora Lentivirus plasmid |
| ORF Viral Vector | vGMAD000633 | house mouse Rora Adenovirus particle |
| ORF Viral Vector | vGMLPm001751 | mouse Rora Lentivirus particle |
Target information
| Target ID | GM-T43206 |
| Target Name | RORA |
| Gene ID | 6095,19883,300807,704014,119866906,101099721,535597,100147460 |
| Gene Symbol and Synonyms | 9530021D13Rik,IDDECA,LOC119866906,nmf267,NR1F1,ROR1,ROR2,ROR3,RORA,RORa1,RORalpha,RZR-ALPHA,RZRA,sg,staggerer,tmgc26 |
| Uniprot Accession | P35398 |
| Uniprot Entry Name | RORA_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000069667 |
| Target Classification | N/A |
The target: RORA, gene name: RORA, also named as IDDECA, NR1F1, ROR1, ROR2, ROR3, RZR-ALPHA, RZRA. The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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