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Anti-FGFP1/ FGFBP1/ FGF-BP monoclonal antibody
Anti-FGFP1/ FGFBP1/ FGF-BP antibody for FACS & in-vivo assay
Go to FGFBP1/FGFBP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T43605-Ab-1/ GM-Tg-hg-T43605-Ab-2 | Anti-Human FGFBP1 monoclonal antibody | Human |
| GM-Tg-rg-T43605-Ab-1/ GM-Tg-rg-T43605-Ab-2 | Anti-Rat FGFBP1 monoclonal antibody | Rat |
| GM-Tg-mg-T43605-Ab-1/ GM-Tg-mg-T43605-Ab-2 | Anti-Mouse FGFBP1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T43605-Ab-1/ GM-Tg-cynog-T43605-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FGFBP1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T43605-Ab-1/ GM-Tg-felg-T43605-Ab-2 | Anti-Feline FGFBP1 monoclonal antibody | Feline |
| GM-Tg-cang-T43605-Ab-1/ GM-Tg-cang-T43605-Ab-2 | Anti-Canine FGFBP1 monoclonal antibody | Canine |
| GM-Tg-bovg-T43605-Ab-1/ GM-Tg-bovg-T43605-Ab-2 | Anti-Bovine FGFBP1 monoclonal antibody | Bovine |
| GM-Tg-equg-T43605-Ab-1/ GM-Tg-equg-T43605-Ab-2 | Anti-Equine FGFBP1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T43605-Ab-1/ GM-Tg-hg-T43605-Ab-2; GM-Tg-rg-T43605-Ab-1/ GM-Tg-rg-T43605-Ab-2; GM-Tg-mg-T43605-Ab-1/ GM-Tg-mg-T43605-Ab-2; GM-Tg-cynog-T43605-Ab-1/ GM-Tg-cynog-T43605-Ab-2; GM-Tg-felg-T43605-Ab-1/ GM-Tg-felg-T43605-Ab-2; GM-Tg-cang-T43605-Ab-1/ GM-Tg-cang-T43605-Ab-2; GM-Tg-bovg-T43605-Ab-1/ GM-Tg-bovg-T43605-Ab-2; GM-Tg-equg-T43605-Ab-1/ GM-Tg-equg-T43605-Ab-2 |
| Products Name | Anti-FGFBP1 monoclonal antibody |
| Format | mab |
| Target Name | FGFBP1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-FGFBP1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species FGFP1/ FGFBP1/ FGF-BP VLP (virus-like particle) (Products Developing) |
| Cytokine | GM-Tg-g-T43605-Ag-1 | fibroblast growth factor binding protein 1 (FGFBP1) protein |
| ORF Viral Vector | vGMLP001293 | human FGFBP1 Lentivirus particle |
| ORF Viral Vector | vGMLP003920 | human FGFBP1 Lentivirus particle |
| ORF Viral Vector | pGMLP003986 | human FGFBP1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP003986 | human FGFBP1 Lentivirus particle |
| ORF Viral Vector | pGMLP001293 | human FGFBP1 Lentivirus plasmid |
| ORF Viral Vector | pGMLP003920 | human FGFBP1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000373 | mouse Fgfbp1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000373 | mouse Fgfbp1 Lentivirus particle |
Target information
| Target ID | GM-T43605 |
| Target Name | FGFBP1 |
| Gene ID | 9982,14181,64535,714505,488818,101094417 |
| Gene Symbol and Synonyms | FGF-BP,FGF-BP1,FGFBP,FGFBP-1,FGFBP1,HBP17 |
| Uniprot Accession | Q14512,Q9QY10 |
| Uniprot Entry Name | FGFP1_HUMAN,FGFP1_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000137440 |
| Target Classification | N/A |
The target: FGFBP1, gene name: FGFBP1, also named as FGF-BP, FGF-BP1, FGFBP, FGFBP-1, HBP17. This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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