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Anti-FST/ FS functional antibody
Anti-FST/ FS functional antibody for cell culture, ELISA & in-vivo assay
Go to FST/FST products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T43901-Ab-1/ GM-Tg-hg-T43901-Ab-2 | Anti-Human FST monoclonal antibody | Human |
| GM-Tg-rg-T43901-Ab-1/ GM-Tg-rg-T43901-Ab-2 | Anti-Rat FST monoclonal antibody | Rat |
| GM-Tg-mg-T43901-Ab-1/ GM-Tg-mg-T43901-Ab-2 | Anti-Mouse FST monoclonal antibody | Mouse |
| GM-Tg-cynog-T43901-Ab-1/ GM-Tg-cynog-T43901-Ab-2 | Anti-Cynomolgus/ Rhesus macaque FST monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T43901-Ab-1/ GM-Tg-felg-T43901-Ab-2 | Anti-Feline FST monoclonal antibody | Feline |
| GM-Tg-cang-T43901-Ab-1/ GM-Tg-cang-T43901-Ab-2 | Anti-Canine FST monoclonal antibody | Canine |
| GM-Tg-bovg-T43901-Ab-1/ GM-Tg-bovg-T43901-Ab-2 | Anti-Bovine FST monoclonal antibody | Bovine |
| GM-Tg-equg-T43901-Ab-1/ GM-Tg-equg-T43901-Ab-2 | Anti-Equine FST monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T43901-Ab-1/ GM-Tg-hg-T43901-Ab-2; GM-Tg-rg-T43901-Ab-1/ GM-Tg-rg-T43901-Ab-2; GM-Tg-mg-T43901-Ab-1/ GM-Tg-mg-T43901-Ab-2; GM-Tg-cynog-T43901-Ab-1/ GM-Tg-cynog-T43901-Ab-2; GM-Tg-felg-T43901-Ab-1/ GM-Tg-felg-T43901-Ab-2; GM-Tg-cang-T43901-Ab-1/ GM-Tg-cang-T43901-Ab-2; GM-Tg-bovg-T43901-Ab-1/ GM-Tg-bovg-T43901-Ab-2; GM-Tg-equg-T43901-Ab-1/ GM-Tg-equg-T43901-Ab-2 |
| Products Name | Anti-FST monoclonal antibody |
| Format | mab |
| Target Name | FST |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-FST benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T43901-Ag-1 | Recombinant multi-species FST/ FS protein |
| Cytokine | GM-Tg-g-T43901-Ag-1 | follistatin (FST) protein |
| ORF Viral Vector | vGMLP003562 | human FST Lentivirus particle |
| ORF Viral Vector | pGMLP003562 | human FST Lentivirus plasmid |
| ORF Viral Vector | pGMAAV000282 | house mouse Fst AAV plasmid |
| ORF Viral Vector | pGMLPm001597 | mouse Fst Lentivirus plasmid |
| ORF Viral Vector | vGMAAV000282 | house mouse Fst AAV particle |
| ORF Viral Vector | vGMLPm001597 | mouse Fst Lentivirus particle |
Target information
| Target ID | GM-T43901 |
| Target Name | FST |
| Gene ID | 10468,14313,24373,707420,479336,101089985,327681,100033825 |
| Gene Symbol and Synonyms | FOL1,FS,FST,Fst-288,RATFOL1 |
| Uniprot Accession | P19883,P21674,P50291,O62650 |
| Uniprot Entry Name | FST_HUMAN,FST_RAT,FST_BOVIN,FST_HORSE |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, Cytokine Target |
| Disease | ovarian cancer |
| Gene Ensembl | ENSG00000134363 |
| Target Classification | N/A |
The target: FST, gene name: FST, also named as FS. Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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