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Anti-VEGFC/ Flt4-L/ LMPH1D functional antibody
Anti-VEGFC/ Flt4-L/ LMPH1D functional antibody for cell culture, ELISA & in-vivo assay
Go to VEGFC/VEGFC products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T51425-Ab-1/ GM-Tg-hg-T51425-Ab-2 | Anti-Human VEGFC monoclonal antibody | Human |
| GM-Tg-rg-T51425-Ab-1/ GM-Tg-rg-T51425-Ab-2 | Anti-Rat VEGFC monoclonal antibody | Rat |
| GM-Tg-mg-T51425-Ab-1/ GM-Tg-mg-T51425-Ab-2 | Anti-Mouse VEGFC monoclonal antibody | Mouse |
| GM-Tg-cynog-T51425-Ab-1/ GM-Tg-cynog-T51425-Ab-2 | Anti-Cynomolgus/ Rhesus macaque VEGFC monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T51425-Ab-1/ GM-Tg-felg-T51425-Ab-2 | Anti-Feline VEGFC monoclonal antibody | Feline |
| GM-Tg-cang-T51425-Ab-1/ GM-Tg-cang-T51425-Ab-2 | Anti-Canine VEGFC monoclonal antibody | Canine |
| GM-Tg-bovg-T51425-Ab-1/ GM-Tg-bovg-T51425-Ab-2 | Anti-Bovine VEGFC monoclonal antibody | Bovine |
| GM-Tg-equg-T51425-Ab-1/ GM-Tg-equg-T51425-Ab-2 | Anti-Equine VEGFC monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T51425-Ab-1/ GM-Tg-hg-T51425-Ab-2; GM-Tg-rg-T51425-Ab-1/ GM-Tg-rg-T51425-Ab-2; GM-Tg-mg-T51425-Ab-1/ GM-Tg-mg-T51425-Ab-2; GM-Tg-cynog-T51425-Ab-1/ GM-Tg-cynog-T51425-Ab-2; GM-Tg-felg-T51425-Ab-1/ GM-Tg-felg-T51425-Ab-2; GM-Tg-cang-T51425-Ab-1/ GM-Tg-cang-T51425-Ab-2; GM-Tg-bovg-T51425-Ab-1/ GM-Tg-bovg-T51425-Ab-2; GM-Tg-equg-T51425-Ab-1/ GM-Tg-equg-T51425-Ab-2 |
| Products Name | Anti-VEGFC monoclonal antibody |
| Format | mab |
| Target Name | VEGFC |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-VEGFC benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T51425-Ag-1 | Recombinant multi-species VEGFC/ Flt4-L/ LMPH1D protein |
| Cytokine | GM-Tg-g-T51425-Ag-1 | Vascular endothelial growth factor C (VEGFC) protein |
| ORF Viral Vector | vGMAP000194 | Human VEGFC Adenovirus particle |
| ORF Viral Vector | pGMAP000194 | Human VEGFC Adenovirus plasmid |
| ORF Viral Vector | pGMLPm001747 | mouse Vegfc Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001747 | mouse Vegfc Lentivirus particle |
Target information
| Target ID | GM-T51425 |
| Target Name | VEGFC |
| Gene ID | 7424,22341,114111,699502,482932,101085368,282122,100060890 |
| Gene Symbol and Synonyms | Flt4-L,LMPH1D,LMPHM4,VEGF-C,VEGFC,VRP |
| Uniprot Accession | P49767,O35757 |
| Uniprot Entry Name | VEGFC_HUMAN,VEGFC_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, Cytokine Target |
| Disease | Breast Cancer |
| Gene Ensembl | ENSG00000150630 |
| Target Classification | N/A |
The target: VEGFC, gene name: VEGFC, also named as Flt4-L, LMPH1D, VRP. The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors. [provided by RefSeq, Apr 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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