Anti-CSNK2A1 monoclonal antibody

Pre-made anti-CSNK2A1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to CSNK2A1/CSNK2A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T51565-Ab-1/ GM-Tg-hg-T51565-Ab-2Anti-Human CSNK2A1 monoclonal antibodyHuman
GM-Tg-rg-T51565-Ab-1/ GM-Tg-rg-T51565-Ab-2Anti-Rat CSNK2A1 monoclonal antibodyRat
GM-Tg-mg-T51565-Ab-1/ GM-Tg-mg-T51565-Ab-2Anti-Mouse CSNK2A1 monoclonal antibodyMouse
GM-Tg-cynog-T51565-Ab-1/ GM-Tg-cynog-T51565-Ab-2Anti-Cynomolgus/ Rhesus macaque CSNK2A1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T51565-Ab-1/ GM-Tg-felg-T51565-Ab-2Anti-Feline CSNK2A1 monoclonal antibodyFeline
GM-Tg-cang-T51565-Ab-1/ GM-Tg-cang-T51565-Ab-2Anti-Canine CSNK2A1 monoclonal antibodyCanine
GM-Tg-bovg-T51565-Ab-1/ GM-Tg-bovg-T51565-Ab-2Anti-Bovine CSNK2A1 monoclonal antibodyBovine
GM-Tg-equg-T51565-Ab-1/ GM-Tg-equg-T51565-Ab-2Anti-Equine CSNK2A1 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T51565-Ab-1/ GM-Tg-hg-T51565-Ab-2; GM-Tg-rg-T51565-Ab-1/ GM-Tg-rg-T51565-Ab-2;
GM-Tg-mg-T51565-Ab-1/ GM-Tg-mg-T51565-Ab-2; GM-Tg-cynog-T51565-Ab-1/ GM-Tg-cynog-T51565-Ab-2;
GM-Tg-felg-T51565-Ab-1/ GM-Tg-felg-T51565-Ab-2; GM-Tg-cang-T51565-Ab-1/ GM-Tg-cang-T51565-Ab-2;
GM-Tg-bovg-T51565-Ab-1/ GM-Tg-bovg-T51565-Ab-2; GM-Tg-equg-T51565-Ab-1/ GM-Tg-equg-T51565-Ab-2
Products NameAnti-CSNK2A1 monoclonal antibody
Formatmab
Target NameCSNK2A1
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-CSNK2A1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T51565-Ag-1Recombinant multi-species CSK21/ CSNK2A1/ CK2A1 protein
    ORF Viral VectorvGMAP000354Human CSNK2A1 Adenovirus particle
    ORF Viral VectorpGMAP000354Human CSNK2A1 Adenovirus plasmid
    ORF Viral VectorpGMLPm002611mouse Csnk2a1 Lentivirus plasmid
    ORF Viral VectorvGMLPm002611mouse Csnk2a1 Lentivirus particle


    Target information

    Target IDGM-T51565
    Target NameCSNK2A1
    Gene ID1457,12995,116549,714841,477185,101084186,282419,100067965
    Gene Symbol and SynonymsCK II alpha,CK2,CK2A1,Cka1,Cka2,CKII,CSNK2A1,Csnk2a1-rs4,OCNDS
    Uniprot AccessionP68400,P19139,P68399
    Uniprot Entry NameCSK21_HUMAN,CSK21_RAT,CSK21_BOVIN
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseProstate Cancer
    Gene EnsemblENSG00000101266
    Target ClassificationKinase

    The target: CSNK2A1, gene name: CSNK2A1, also named as CK2A1, CKII, Cka1, Cka2, OCNDS. Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythm. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. Multiple transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Apr 2018].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.