Anti-CSNK2A1 monoclonal antibody
Pre-made anti-CSNK2A1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T51565-Ab-1/ GM-Tg-hg-T51565-Ab-2 | Anti-Human CSNK2A1 monoclonal antibody | Human |
GM-Tg-rg-T51565-Ab-1/ GM-Tg-rg-T51565-Ab-2 | Anti-Rat CSNK2A1 monoclonal antibody | Rat |
GM-Tg-mg-T51565-Ab-1/ GM-Tg-mg-T51565-Ab-2 | Anti-Mouse CSNK2A1 monoclonal antibody | Mouse |
GM-Tg-cynog-T51565-Ab-1/ GM-Tg-cynog-T51565-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CSNK2A1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T51565-Ab-1/ GM-Tg-felg-T51565-Ab-2 | Anti-Feline CSNK2A1 monoclonal antibody | Feline |
GM-Tg-cang-T51565-Ab-1/ GM-Tg-cang-T51565-Ab-2 | Anti-Canine CSNK2A1 monoclonal antibody | Canine |
GM-Tg-bovg-T51565-Ab-1/ GM-Tg-bovg-T51565-Ab-2 | Anti-Bovine CSNK2A1 monoclonal antibody | Bovine |
GM-Tg-equg-T51565-Ab-1/ GM-Tg-equg-T51565-Ab-2 | Anti-Equine CSNK2A1 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-T51565-Ab-1/ GM-Tg-hg-T51565-Ab-2; GM-Tg-rg-T51565-Ab-1/ GM-Tg-rg-T51565-Ab-2; GM-Tg-mg-T51565-Ab-1/ GM-Tg-mg-T51565-Ab-2; GM-Tg-cynog-T51565-Ab-1/ GM-Tg-cynog-T51565-Ab-2; GM-Tg-felg-T51565-Ab-1/ GM-Tg-felg-T51565-Ab-2; GM-Tg-cang-T51565-Ab-1/ GM-Tg-cang-T51565-Ab-2; GM-Tg-bovg-T51565-Ab-1/ GM-Tg-bovg-T51565-Ab-2; GM-Tg-equg-T51565-Ab-1/ GM-Tg-equg-T51565-Ab-2 |
Products Name | Anti-CSNK2A1 monoclonal antibody |
Format | mab |
Target Name | CSNK2A1 |
Protein Sub-location | Introcelluar Protein |
Category of antibody | Therapeutics Target antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-CSNK2A1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-T51565-Ag-1 | Recombinant multi-species CSK21/ CSNK2A1/ CK2A1 protein |
ORF Viral Vector | vGMAP000354 | Human CSNK2A1 Adenovirus particle |
ORF Viral Vector | pGMAP000354 | Human CSNK2A1 Adenovirus plasmid |
ORF Viral Vector | pGMLPm002611 | mouse Csnk2a1 Lentivirus plasmid |
ORF Viral Vector | vGMLPm002611 | mouse Csnk2a1 Lentivirus particle |
Target information
Target ID | GM-T51565 |
Target Name | CSNK2A1 |
Gene ID | 1457,12995,116549,714841,477185,101084186,282419,100067965 |
Gene Symbol and Synonyms | CK II alpha,CK2,CK2A1,Cka1,Cka2,CKII,CSNK2A1,Csnk2a1-rs4,OCNDS |
Uniprot Accession | P68400,P19139,P68399 |
Uniprot Entry Name | CSK21_HUMAN,CSK21_RAT,CSK21_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Prostate Cancer |
Gene Ensembl | ENSG00000101266 |
Target Classification | Kinase |
The target: CSNK2A1, gene name: CSNK2A1, also named as CK2A1, CKII, Cka1, Cka2, OCNDS. Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythm. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. Multiple transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Apr 2018].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.