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Anti-S15A2/ SLC15A2/ PEPT2 monoclonal antibody
Anti-S15A2/ SLC15A2/ PEPT2 antibody for FACS & in-vivo assay
Go to SLC15A2/SLC15A2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T52067-Ab-1/ GM-Tg-hg-T52067-Ab-2 | Anti-Human SLC15A2 monoclonal antibody | Human |
| GM-Tg-rg-T52067-Ab-1/ GM-Tg-rg-T52067-Ab-2 | Anti-Rat SLC15A2 monoclonal antibody | Rat |
| GM-Tg-mg-T52067-Ab-1/ GM-Tg-mg-T52067-Ab-2 | Anti-Mouse SLC15A2 monoclonal antibody | Mouse |
| GM-Tg-cynog-T52067-Ab-1/ GM-Tg-cynog-T52067-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC15A2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T52067-Ab-1/ GM-Tg-felg-T52067-Ab-2 | Anti-Feline SLC15A2 monoclonal antibody | Feline |
| GM-Tg-cang-T52067-Ab-1/ GM-Tg-cang-T52067-Ab-2 | Anti-Canine SLC15A2 monoclonal antibody | Canine |
| GM-Tg-bovg-T52067-Ab-1/ GM-Tg-bovg-T52067-Ab-2 | Anti-Bovine SLC15A2 monoclonal antibody | Bovine |
| GM-Tg-equg-T52067-Ab-1/ GM-Tg-equg-T52067-Ab-2 | Anti-Equine SLC15A2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T52067-Ab-1/ GM-Tg-hg-T52067-Ab-2; GM-Tg-rg-T52067-Ab-1/ GM-Tg-rg-T52067-Ab-2; GM-Tg-mg-T52067-Ab-1/ GM-Tg-mg-T52067-Ab-2; GM-Tg-cynog-T52067-Ab-1/ GM-Tg-cynog-T52067-Ab-2; GM-Tg-felg-T52067-Ab-1/ GM-Tg-felg-T52067-Ab-2; GM-Tg-cang-T52067-Ab-1/ GM-Tg-cang-T52067-Ab-2; GM-Tg-bovg-T52067-Ab-1/ GM-Tg-bovg-T52067-Ab-2; GM-Tg-equg-T52067-Ab-1/ GM-Tg-equg-T52067-Ab-2 |
| Products Name | Anti-SLC15A2 monoclonal antibody |
| Format | mab |
| Target Name | SLC15A2 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SLC15A2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species S15A2/ SLC15A2/ PEPT2 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLV000078 | human SLC15A2 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000078 | human SLC15A2 Lentivirus particle |
Target information
| Target ID | GM-T52067 |
| Target Name | SLC15A2 |
| Gene ID | 6565,57738,60577,574375,488006,101085825,100070712 |
| Gene Symbol and Synonyms | 8430408C16Rik,PEPT2,SLC15A2 |
| Uniprot Accession | Q16348,Q63424 |
| Uniprot Entry Name | S15A2_HUMAN,S15A2_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000163406 |
| Target Classification | N/A |
The target: SLC15A2, gene name: SLC15A2, also named as PEPT2. The mammalian kidney expresses a proton-coupled peptide transporter that is responsible for the absorption of small peptides, as well as beta-lactam antibiotics and other peptide-like drugs, from the tubular filtrate. This transporter, SLC15A2, belongs to the same gene family as SLC15A1 (MIM 600544), the proton-coupled peptide transporter found in the small intestine (Liu et al, 1995 [PubMed 7756356]).[supplied by OMIM, Feb 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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