Anti-SSR2/ SSTR2 monoclonal antibody

Anti-SSR2/ SSTR2 antibody for FACS & in-vivo assay

Target products collectionGo to SSTR2/SSTR2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T53024-Ab-1/ GM-Tg-hg-T53024-Ab-2Anti-Human SSTR2 monoclonal antibodyHuman
GM-Tg-rg-T53024-Ab-1/ GM-Tg-rg-T53024-Ab-2Anti-Rat SSTR2 monoclonal antibodyRat
GM-Tg-mg-T53024-Ab-1/ GM-Tg-mg-T53024-Ab-2Anti-Mouse SSTR2 monoclonal antibodyMouse
GM-Tg-cynog-T53024-Ab-1/ GM-Tg-cynog-T53024-Ab-2Anti-Cynomolgus/ Rhesus macaque SSTR2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T53024-Ab-1/ GM-Tg-felg-T53024-Ab-2Anti-Feline SSTR2 monoclonal antibodyFeline
GM-Tg-cang-T53024-Ab-1/ GM-Tg-cang-T53024-Ab-2Anti-Canine SSTR2 monoclonal antibodyCanine
GM-Tg-bovg-T53024-Ab-1/ GM-Tg-bovg-T53024-Ab-2Anti-Bovine SSTR2 monoclonal antibodyBovine
GM-Tg-equg-T53024-Ab-1/ GM-Tg-equg-T53024-Ab-2Anti-Equine SSTR2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T53024-Ab-1/ GM-Tg-hg-T53024-Ab-2; GM-Tg-rg-T53024-Ab-1/ GM-Tg-rg-T53024-Ab-2;
GM-Tg-mg-T53024-Ab-1/ GM-Tg-mg-T53024-Ab-2; GM-Tg-cynog-T53024-Ab-1/ GM-Tg-cynog-T53024-Ab-2;
GM-Tg-felg-T53024-Ab-1/ GM-Tg-felg-T53024-Ab-2; GM-Tg-cang-T53024-Ab-1/ GM-Tg-cang-T53024-Ab-2;
GM-Tg-bovg-T53024-Ab-1/ GM-Tg-bovg-T53024-Ab-2; GM-Tg-equg-T53024-Ab-1/ GM-Tg-equg-T53024-Ab-2
Products NameAnti-SSTR2 monoclonal antibody
Formatmab
Target NameSSTR2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SSTR2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    BiosimilarGMP-Bios-ab-570Pre-Made Tidutamab biosimilar, Bispecific Mixed mAb and scFv, Anti-SSTR2;CD3E Antibody: Anti-T3E/TCRE/IMD18/CD3epsilon therapeutic antibody
    Target AntigenProducts DevelopingMulti-species SSR2/ SSTR2 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP000605human SSTR2 Lentivirus particle
    ORF Viral VectorpGMLP000605human SSTR2 Lentivirus plasmid
    ORF Viral VectorpGMLPm002925mouse Sstr2 Lentivirus plasmid
    ORF Viral VectorvGMLPm002925mouse Sstr2 Lentivirus particle


    Target information

    Target IDGM-T53024
    Target NameSSTR2
    Gene ID6752,20606,54305,695526,403472,101090974,282083,100052744
    Gene Symbol and SynonymsSmstr-2,Smstr2,SRIF-1,SS2R,SST2,SSTR-2,SSTR2
    Uniprot AccessionP30874,P30680,Q49LX6,P34993
    Uniprot Entry NameSSR2_HUMAN,SSR2_RAT,SSR2_CANLF,SSR2_BOVIN
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target, Immuno-oncology Target, INN Index
    DiseaseCancer
    Gene EnsemblENSG00000180616
    Target ClassificationCheckpoint-Immuno Oncology, GPCR, Tumor-associated antigen (TAA)

    The target: SSTR2, gene name: SSTR2, also named as . Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.