- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-PSMD10 monoclonal antibody
Pre-made anti-PSMD10 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to PSMD10/PSMD10 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T53890-Ab-1/ GM-Tg-hg-T53890-Ab-2 | Anti-Human PSMD10 monoclonal antibody | Human |
| GM-Tg-rg-T53890-Ab-1/ GM-Tg-rg-T53890-Ab-2 | Anti-Rat PSMD10 monoclonal antibody | Rat |
| GM-Tg-mg-T53890-Ab-1/ GM-Tg-mg-T53890-Ab-2 | Anti-Mouse PSMD10 monoclonal antibody | Mouse |
| GM-Tg-cynog-T53890-Ab-1/ GM-Tg-cynog-T53890-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PSMD10 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T53890-Ab-1/ GM-Tg-felg-T53890-Ab-2 | Anti-Feline PSMD10 monoclonal antibody | Feline |
| GM-Tg-cang-T53890-Ab-1/ GM-Tg-cang-T53890-Ab-2 | Anti-Canine PSMD10 monoclonal antibody | Canine |
| GM-Tg-bovg-T53890-Ab-1/ GM-Tg-bovg-T53890-Ab-2 | Anti-Bovine PSMD10 monoclonal antibody | Bovine |
| GM-Tg-equg-T53890-Ab-1/ GM-Tg-equg-T53890-Ab-2 | Anti-Equine PSMD10 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T53890-Ab-1/ GM-Tg-hg-T53890-Ab-2; GM-Tg-rg-T53890-Ab-1/ GM-Tg-rg-T53890-Ab-2; GM-Tg-mg-T53890-Ab-1/ GM-Tg-mg-T53890-Ab-2; GM-Tg-cynog-T53890-Ab-1/ GM-Tg-cynog-T53890-Ab-2; GM-Tg-felg-T53890-Ab-1/ GM-Tg-felg-T53890-Ab-2; GM-Tg-cang-T53890-Ab-1/ GM-Tg-cang-T53890-Ab-2; GM-Tg-bovg-T53890-Ab-1/ GM-Tg-bovg-T53890-Ab-2; GM-Tg-equg-T53890-Ab-1/ GM-Tg-equg-T53890-Ab-2 |
| Products Name | Anti-PSMD10 monoclonal antibody |
| Format | mab |
| Target Name | PSMD10 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-PSMD10 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T53890-Ag-1 | Recombinant multi-species PSD10/ PSMD10/ dJ889N15.2 protein |
| ORF Viral Vector | pGMLP000500 | human PSMD10 Lentivirus plasmid |
| ORF Viral Vector | vGMAP000467 | Human PSMD10 Adenovirus particle |
| ORF Viral Vector | pGMAP000467 | Human PSMD10 Adenovirus plasmid |
| ORF Viral Vector | vGMLP000500 | human PSMD10 Lentivirus particle |
| ORF Viral Vector | pGMLPm002432 | mouse Psmd10 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002432 | mouse Psmd10 Lentivirus particle |
Target information
| Target ID | GM-T53890 |
| Target Name | PSMD10 |
| Gene ID | 5716,53380,116722,703596,481014,101087906,535414,100054590 |
| Gene Symbol and Synonyms | dJ889N15.2,p28,p28(GANK),p28Gank,PSMD10 |
| Uniprot Accession | O75832,Q9Z2X3 |
| Uniprot Entry Name | PSD10_HUMAN,PSD10_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000101843 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: PSMD10, gene name: PSMD10, also named as dJ889N15.2, p28, p28(GANK). This gene encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. The 26S proteosome complex is required for ubiquitin-dependent protein degradation. This protein is a non-ATPase subunit that may be involved in protein-protein interactions. Aberrant expression of this gene may paly a role in tumorigenesis. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.[provided by RefSeq, Mar 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
