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Anti-XLRS1/ RS1/ RS functional antibody
Anti-XLRS1/ RS1/ RS functional antibody for cell culture, ELISA & in-vivo assay
Go to RS1/RS1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T54031-Ab-1/ GM-Tg-hg-T54031-Ab-2 | Anti-Human RS1 monoclonal antibody | Human |
| GM-Tg-rg-T54031-Ab-1/ GM-Tg-rg-T54031-Ab-2 | Anti-Rat RS1 monoclonal antibody | Rat |
| GM-Tg-mg-T54031-Ab-1/ GM-Tg-mg-T54031-Ab-2 | Anti-Mouse RS1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T54031-Ab-1/ GM-Tg-cynog-T54031-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RS1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T54031-Ab-1/ GM-Tg-felg-T54031-Ab-2 | Anti-Feline RS1 monoclonal antibody | Feline |
| GM-Tg-cang-T54031-Ab-1/ GM-Tg-cang-T54031-Ab-2 | Anti-Canine RS1 monoclonal antibody | Canine |
| GM-Tg-bovg-T54031-Ab-1/ GM-Tg-bovg-T54031-Ab-2 | Anti-Bovine RS1 monoclonal antibody | Bovine |
| GM-Tg-equg-T54031-Ab-1/ GM-Tg-equg-T54031-Ab-2 | Anti-Equine RS1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T54031-Ab-1/ GM-Tg-hg-T54031-Ab-2; GM-Tg-rg-T54031-Ab-1/ GM-Tg-rg-T54031-Ab-2; GM-Tg-mg-T54031-Ab-1/ GM-Tg-mg-T54031-Ab-2; GM-Tg-cynog-T54031-Ab-1/ GM-Tg-cynog-T54031-Ab-2; GM-Tg-felg-T54031-Ab-1/ GM-Tg-felg-T54031-Ab-2; GM-Tg-cang-T54031-Ab-1/ GM-Tg-cang-T54031-Ab-2; GM-Tg-bovg-T54031-Ab-1/ GM-Tg-bovg-T54031-Ab-2; GM-Tg-equg-T54031-Ab-1/ GM-Tg-equg-T54031-Ab-2 |
| Products Name | Anti-RS1 monoclonal antibody |
| Format | mab |
| Target Name | RS1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-RS1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T54031-Ag-1 | Recombinant multi-species XLRS1/ RS1/ RS protein |
| ORF Viral Vector | vGMAAV000362 | human RS1 AAV particle |
| ORF Viral Vector | pGMAAV000362 | human RS1 AAV plasmid |
| ORF Viral Vector | pGMLP002955 | human RS1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP002955 | human RS1 Lentivirus particle |
| ORF Viral Vector | pGMLPm001304 | mouse Rs1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001304 | mouse Rs1 Lentivirus particle |
Target information
| Target ID | GM-T54031 |
| Target Name | RS1 |
| Gene ID | 6247,20147,100125595,100423325,119868374,101088816,615193,100058084 |
| Gene Symbol and Synonyms | RS,RS1,Rs1h,tmgc1,XLRS1 |
| Uniprot Accession | O15537 |
| Uniprot Entry Name | XLRS1_HUMAN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000102104 |
| Target Classification | N/A |
The target: RS1, gene name: RS1, also named as RS, XLRS1. This gene encodes an extracellular protein that plays a crucial role in the cellular organization of the retina. The encoded protein is assembled and secreted from photoreceptors and bipolar cells as a homo-oligomeric protein complex. Mutations in this gene are responsible for X-linked retinoschisis, a common, early-onset macular degeneration in males that results in a splitting of the inner layers of the retina and severe loss in vision. [provided by RefSeq, Oct 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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