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Anti-RET4/ RBP4/ MCOPCB10 functional antibody
Anti-RET4/ RBP4/ MCOPCB10 functional antibody for cell culture, ELISA & in-vivo assay
Go to RBP4/RBP4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T55703-Ab-1/ GM-Tg-hg-T55703-Ab-2 | Anti-Human RBP4 monoclonal antibody | Human |
| GM-Tg-rg-T55703-Ab-1/ GM-Tg-rg-T55703-Ab-2 | Anti-Rat RBP4 monoclonal antibody | Rat |
| GM-Tg-mg-T55703-Ab-1/ GM-Tg-mg-T55703-Ab-2 | Anti-Mouse RBP4 monoclonal antibody | Mouse |
| GM-Tg-cynog-T55703-Ab-1/ GM-Tg-cynog-T55703-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RBP4 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T55703-Ab-1/ GM-Tg-felg-T55703-Ab-2 | Anti-Feline RBP4 monoclonal antibody | Feline |
| GM-Tg-cang-T55703-Ab-1/ GM-Tg-cang-T55703-Ab-2 | Anti-Canine RBP4 monoclonal antibody | Canine |
| GM-Tg-bovg-T55703-Ab-1/ GM-Tg-bovg-T55703-Ab-2 | Anti-Bovine RBP4 monoclonal antibody | Bovine |
| GM-Tg-equg-T55703-Ab-1/ GM-Tg-equg-T55703-Ab-2 | Anti-Equine RBP4 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T55703-Ab-1/ GM-Tg-hg-T55703-Ab-2; GM-Tg-rg-T55703-Ab-1/ GM-Tg-rg-T55703-Ab-2; GM-Tg-mg-T55703-Ab-1/ GM-Tg-mg-T55703-Ab-2; GM-Tg-cynog-T55703-Ab-1/ GM-Tg-cynog-T55703-Ab-2; GM-Tg-felg-T55703-Ab-1/ GM-Tg-felg-T55703-Ab-2; GM-Tg-cang-T55703-Ab-1/ GM-Tg-cang-T55703-Ab-2; GM-Tg-bovg-T55703-Ab-1/ GM-Tg-bovg-T55703-Ab-2; GM-Tg-equg-T55703-Ab-1/ GM-Tg-equg-T55703-Ab-2 |
| Products Name | Anti-RBP4 monoclonal antibody |
| Format | mab |
| Target Name | RBP4 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-RBP4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T55703-Ag-1 | Recombinant multi-species RET4/ RBP4/ MCOPCB10 protein |
| Cytokine | GM-Tg-g-T55703-Ag-1 | retinol binding protein 4 (RBP4) protein |
| ORF Viral Vector | pGMLP001901 | human RBP4 Lentivirus plasmid |
| ORF Viral Vector | vGMLP001901 | human RBP4 Lentivirus particle |
| ORF Viral Vector | pGMAD000074 | mouse Rbp4 Adenovirus plasmid |
| ORF Viral Vector | vGMAD000074 | mouse Rbp4 Adenovirus particle |
Target information
| Target ID | GM-T55703 |
| Target Name | RBP4 |
| Gene ID | 5950,19662,25703,701270,477775,101094377,281444 |
| Gene Symbol and Synonyms | fCP1,MCOPCB10,PRBP,RBP,Rbp-4,RBP4,RBPA,RDCCAS |
| Uniprot Accession | P02753,P04916,M5AXY1,P18902 |
| Uniprot Entry Name | RET4_HUMAN,RET4_RAT,RET4_FELCA,RET4_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, Diagnostics Biomarker, Cytokine Target |
| Disease | Lung Cancer, Complications of kidney transplant, Acute kidney failure, Chronic Kidney Disease, Dent disease, Diabetic Nephropathy, Nephrotic syndrome, Nephrotic syndrome with focal and segmental glomerular lesions, Perinatal necrotizing enterocolitis, Type 1 diabetes mellitus, Type 2 diabetes mellitus |
| Gene Ensembl | ENSG00000138207 |
| Target Classification | N/A |
The target: RBP4, gene name: RBP4, also named as MCOPCB10, RDCCAS. This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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