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Anti-p38 beta monoclonal antibody
Pre-made anti-p38 beta monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to p38 beta/MAPK11 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T55729-Ab-1/ GM-Tg-hg-T55729-Ab-2 | Anti-Human p38 beta/MAPK11 monoclonal antibody | Human |
| GM-Tg-rg-T55729-Ab-1/ GM-Tg-rg-T55729-Ab-2 | Anti-Rat p38 beta/MAPK11 monoclonal antibody | Rat |
| GM-Tg-mg-T55729-Ab-1/ GM-Tg-mg-T55729-Ab-2 | Anti-Mouse p38 beta/MAPK11 monoclonal antibody | Mouse |
| GM-Tg-cynog-T55729-Ab-1/ GM-Tg-cynog-T55729-Ab-2 | Anti-Cynomolgus/ Rhesus macaque p38 beta/MAPK11 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T55729-Ab-1/ GM-Tg-felg-T55729-Ab-2 | Anti-Feline p38 beta/MAPK11 monoclonal antibody | Feline |
| GM-Tg-cang-T55729-Ab-1/ GM-Tg-cang-T55729-Ab-2 | Anti-Canine p38 beta/MAPK11 monoclonal antibody | Canine |
| GM-Tg-bovg-T55729-Ab-1/ GM-Tg-bovg-T55729-Ab-2 | Anti-Bovine p38 beta/MAPK11 monoclonal antibody | Bovine |
| GM-Tg-equg-T55729-Ab-1/ GM-Tg-equg-T55729-Ab-2 | Anti-Equine p38 beta/MAPK11 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T55729-Ab-1/ GM-Tg-hg-T55729-Ab-2; GM-Tg-rg-T55729-Ab-1/ GM-Tg-rg-T55729-Ab-2; GM-Tg-mg-T55729-Ab-1/ GM-Tg-mg-T55729-Ab-2; GM-Tg-cynog-T55729-Ab-1/ GM-Tg-cynog-T55729-Ab-2; GM-Tg-felg-T55729-Ab-1/ GM-Tg-felg-T55729-Ab-2; GM-Tg-cang-T55729-Ab-1/ GM-Tg-cang-T55729-Ab-2; GM-Tg-bovg-T55729-Ab-1/ GM-Tg-bovg-T55729-Ab-2; GM-Tg-equg-T55729-Ab-1/ GM-Tg-equg-T55729-Ab-2 |
| Products Name | Anti-p38 beta/MAPK11 monoclonal antibody |
| Format | mab |
| Target Name | p38 beta |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-p38 beta monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T55729-Ag-1 | Recombinant multi-species MK11/ p38 beta/ MAPK11 protein |
| ORF Viral Vector | pGMLPm002918 | mouse Mapk11 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002918 | mouse Mapk11 Lentivirus particle |
Target information
| Target ID | GM-T55729 |
| Target Name | p38 beta |
| Gene ID | 5600,19094,689314,715794,607019,105260786,618906,100056278 |
| Gene Symbol and Synonyms | MAPK11,p38-2,P38B,p38Beta,P38BETA2,PRKM11,SAPK2,SAPK2B |
| Uniprot Accession | Q15759 |
| Uniprot Entry Name | MK11_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000185386 |
| Target Classification | Kinase |
The target: p38 beta, gene name: MAPK11, also named as P38B, P38BETA2, PRKM11, SAPK2, SAPK2B, p38-2, p38Beta. This gene encodes a member of a family of protein kinases that are involved in the integration of biochemical signals for a wide variety of cellular processes, including cell proliferation, differentiation, transcriptional regulation, and development. The encoded protein can be activated by proinflammatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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