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Anti-LSS monoclonal antibody
Pre-made anti-LSS monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to LSS/LSS products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T56175-Ab-1/ GM-Tg-hg-T56175-Ab-2 | Anti-Human LSS monoclonal antibody | Human |
| GM-Tg-rg-T56175-Ab-1/ GM-Tg-rg-T56175-Ab-2 | Anti-Rat LSS monoclonal antibody | Rat |
| GM-Tg-mg-T56175-Ab-1/ GM-Tg-mg-T56175-Ab-2 | Anti-Mouse LSS monoclonal antibody | Mouse |
| GM-Tg-cynog-T56175-Ab-1/ GM-Tg-cynog-T56175-Ab-2 | Anti-Cynomolgus/ Rhesus macaque LSS monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T56175-Ab-1/ GM-Tg-felg-T56175-Ab-2 | Anti-Feline LSS monoclonal antibody | Feline |
| GM-Tg-cang-T56175-Ab-1/ GM-Tg-cang-T56175-Ab-2 | Anti-Canine LSS monoclonal antibody | Canine |
| GM-Tg-bovg-T56175-Ab-1/ GM-Tg-bovg-T56175-Ab-2 | Anti-Bovine LSS monoclonal antibody | Bovine |
| GM-Tg-equg-T56175-Ab-1/ GM-Tg-equg-T56175-Ab-2 | Anti-Equine LSS monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T56175-Ab-1/ GM-Tg-hg-T56175-Ab-2; GM-Tg-rg-T56175-Ab-1/ GM-Tg-rg-T56175-Ab-2; GM-Tg-mg-T56175-Ab-1/ GM-Tg-mg-T56175-Ab-2; GM-Tg-cynog-T56175-Ab-1/ GM-Tg-cynog-T56175-Ab-2; GM-Tg-felg-T56175-Ab-1/ GM-Tg-felg-T56175-Ab-2; GM-Tg-cang-T56175-Ab-1/ GM-Tg-cang-T56175-Ab-2; GM-Tg-bovg-T56175-Ab-1/ GM-Tg-bovg-T56175-Ab-2; GM-Tg-equg-T56175-Ab-1/ GM-Tg-equg-T56175-Ab-2 |
| Products Name | Anti-LSS monoclonal antibody |
| Format | mab |
| Target Name | LSS |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-LSS monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T56175-Ag-1 | Recombinant multi-species LSS/ CTRCT44/ OSC protein |
| ORF Viral Vector | vGMAAV000025 | human LSS AAV particle |
| ORF Viral Vector | pGMAAV000025 | human LSS AAV plasmid |
| ORF Viral Vector | pGMLPm004817 | mouse Lss Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004817 | mouse Lss Lentivirus particle |
Target information
| Target ID | GM-T56175 |
| Target Name | LSS |
| Gene ID | 4047,16987,81681,709227,491611,101080651,615906,100055292 |
| Gene Symbol and Synonyms | 2810025N20Rik,APMR4,CTRCT44,D10Ertd116e,HYPT14,LSS,OSC |
| Uniprot Accession | P48449,P48450,P84466 |
| Uniprot Entry Name | LSS_HUMAN,LSS_RAT,LSS_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000160285 |
| Target Classification | N/A |
The target: LSS, gene name: LSS, also named as CTRCT44, OSC. The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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