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Anti-PABPC1 monoclonal antibody
Pre-made anti-PABPC1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to PABPC1/PABPC1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T58679-Ab-1/ GM-Tg-hg-T58679-Ab-2 | Anti-Human PABPC1 monoclonal antibody | Human |
| GM-Tg-rg-T58679-Ab-1/ GM-Tg-rg-T58679-Ab-2 | Anti-Rat PABPC1 monoclonal antibody | Rat |
| GM-Tg-mg-T58679-Ab-1/ GM-Tg-mg-T58679-Ab-2 | Anti-Mouse PABPC1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T58679-Ab-1/ GM-Tg-cynog-T58679-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PABPC1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T58679-Ab-1/ GM-Tg-felg-T58679-Ab-2 | Anti-Feline PABPC1 monoclonal antibody | Feline |
| GM-Tg-cang-T58679-Ab-1/ GM-Tg-cang-T58679-Ab-2 | Anti-Canine PABPC1 monoclonal antibody | Canine |
| GM-Tg-bovg-T58679-Ab-1/ GM-Tg-bovg-T58679-Ab-2 | Anti-Bovine PABPC1 monoclonal antibody | Bovine |
| GM-Tg-equg-T58679-Ab-1/ GM-Tg-equg-T58679-Ab-2 | Anti-Equine PABPC1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T58679-Ab-1/ GM-Tg-hg-T58679-Ab-2; GM-Tg-rg-T58679-Ab-1/ GM-Tg-rg-T58679-Ab-2; GM-Tg-mg-T58679-Ab-1/ GM-Tg-mg-T58679-Ab-2; GM-Tg-cynog-T58679-Ab-1/ GM-Tg-cynog-T58679-Ab-2; GM-Tg-felg-T58679-Ab-1/ GM-Tg-felg-T58679-Ab-2; GM-Tg-cang-T58679-Ab-1/ GM-Tg-cang-T58679-Ab-2; GM-Tg-bovg-T58679-Ab-1/ GM-Tg-bovg-T58679-Ab-2; GM-Tg-equg-T58679-Ab-1/ GM-Tg-equg-T58679-Ab-2 |
| Products Name | Anti-PABPC1 monoclonal antibody |
| Format | mab |
| Target Name | PABPC1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-PABPC1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T58679-Ag-1 | Recombinant multi-species PABP1/ PABPC1/ PAB1 protein |
| ORF Viral Vector | pGMLP002152 | human PABPC1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP002152 | human PABPC1 Lentivirus particle |
| ORF Viral Vector | pGMLPm001613 | mouse Pabpc1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001613 | mouse Pabpc1 Lentivirus particle |
Target information
| Target ID | GM-T58679 |
| Target Name | PABPC1 |
| Gene ID | 26986,18458,171350,705847,612751,101083238,282296,100056021 |
| Gene Symbol and Synonyms | ePAB,PAB1,PABP,PABP 1,PABP-1,PABP1,PABPC1,PABPC2,PabpI,PABPL1 |
| Uniprot Accession | P11940,Q9EPH8,P61286 |
| Uniprot Entry Name | PABP1_HUMAN,PABP1_RAT,PABP1_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000070756 |
| Target Classification | N/A |
The target: PABPC1, gene name: PABPC1, also named as PAB1, PABP, PABP1, PABPC2, PABPL1. This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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