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Anti-AAAT/ SLC1A5/ ASCT2 monoclonal antibody
Anti-AAAT/ SLC1A5/ ASCT2 antibody for FACS & in-vivo assay
Go to SLC1A5/SLC1A5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T59493-Ab-1/ GM-Tg-hg-T59493-Ab-2 | Anti-Human SLC1A5 monoclonal antibody | Human |
| GM-Tg-rg-T59493-Ab-1/ GM-Tg-rg-T59493-Ab-2 | Anti-Rat SLC1A5 monoclonal antibody | Rat |
| GM-Tg-mg-T59493-Ab-1/ GM-Tg-mg-T59493-Ab-2 | Anti-Mouse SLC1A5 monoclonal antibody | Mouse |
| GM-Tg-cynog-T59493-Ab-1/ GM-Tg-cynog-T59493-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC1A5 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T59493-Ab-1/ GM-Tg-felg-T59493-Ab-2 | Anti-Feline SLC1A5 monoclonal antibody | Feline |
| GM-Tg-cang-T59493-Ab-1/ GM-Tg-cang-T59493-Ab-2 | Anti-Canine SLC1A5 monoclonal antibody | Canine |
| GM-Tg-bovg-T59493-Ab-1/ GM-Tg-bovg-T59493-Ab-2 | Anti-Bovine SLC1A5 monoclonal antibody | Bovine |
| GM-Tg-equg-T59493-Ab-1/ GM-Tg-equg-T59493-Ab-2 | Anti-Equine SLC1A5 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T59493-Ab-1/ GM-Tg-hg-T59493-Ab-2; GM-Tg-rg-T59493-Ab-1/ GM-Tg-rg-T59493-Ab-2; GM-Tg-mg-T59493-Ab-1/ GM-Tg-mg-T59493-Ab-2; GM-Tg-cynog-T59493-Ab-1/ GM-Tg-cynog-T59493-Ab-2; GM-Tg-felg-T59493-Ab-1/ GM-Tg-felg-T59493-Ab-2; GM-Tg-cang-T59493-Ab-1/ GM-Tg-cang-T59493-Ab-2; GM-Tg-bovg-T59493-Ab-1/ GM-Tg-bovg-T59493-Ab-2; GM-Tg-equg-T59493-Ab-1/ GM-Tg-equg-T59493-Ab-2 |
| Products Name | Anti-SLC1A5 monoclonal antibody |
| Format | mab |
| Target Name | SLC1A5 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SLC1A5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Biosimilar | GMP-Bios-ab-260 | Pre-Made Idactamab biosimilar, Whole mAb, Anti-SLC1A5 Antibody: Anti-AAAT/ASCT2/ATBO/M7V1/M7VS1/R16/RDRC therapeutic antibody |
| Target Antigen | Products Developing | Multi-species AAAT/ SLC1A5/ ASCT2 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMAD000450 | human SLC1A5 Adenovirus plasmid |
| ORF Viral Vector | vGMAD000187 | human SLC1A5 Adenovirus particle |
| ORF Viral Vector | pGMAD000187 | human SLC1A5 Adenovirus plasmid |
| ORF Viral Vector | vGMAD000450 | human SLC1A5 Adenovirus particle |
| ORF Viral Vector | pGMLPm005213 | mouse Slc1a5 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm005213 | mouse Slc1a5 Lentivirus particle |
Target information
| Target ID | GM-T59493 |
| Target Name | SLC1A5 |
| Gene ID | 6510,20514,292657,716843,484425,101090567,282355,100146913 |
| Gene Symbol and Synonyms | AAAT,ASCT2,ATB(0),ATBO,H4-ASCT2,M7V1,M7VS1,R16,RDRC,SLC1A5,Slc1a7 |
| Uniprot Accession | Q15758,D3ZJ25,Q95JC7 |
| Uniprot Entry Name | AAAT_HUMAN,D3ZJ25_RAT,AAAT_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, INN Index |
| Disease | N/A |
| Gene Ensembl | ENSG00000105281 |
| Target Classification | N/A |
The target: SLC1A5, gene name: SLC1A5, also named as AAAT, ASCT2, ATBO, M7V1, M7VS1, R16, RDRC. The SLC1A5 gene encodes a sodium-dependent neutral amino acid transporter that can act as a receptor for RD114/type D retrovirus (Larriba et al., 2001 [PubMed 11781704]).[supplied by OMIM, Jan 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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