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Anti-PDGFC/ FALLOTEIN/ SCDGF monoclonal antibody
Anti-PDGFC/ FALLOTEIN/ SCDGF antibody for FACS & in-vivo assay
Go to PDGFC/PDGFC products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T59510-Ab-1/ GM-Tg-hg-T59510-Ab-2 | Anti-Human PDGFC monoclonal antibody | Human |
| GM-Tg-rg-T59510-Ab-1/ GM-Tg-rg-T59510-Ab-2 | Anti-Rat PDGFC monoclonal antibody | Rat |
| GM-Tg-mg-T59510-Ab-1/ GM-Tg-mg-T59510-Ab-2 | Anti-Mouse PDGFC monoclonal antibody | Mouse |
| GM-Tg-cynog-T59510-Ab-1/ GM-Tg-cynog-T59510-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PDGFC monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T59510-Ab-1/ GM-Tg-felg-T59510-Ab-2 | Anti-Feline PDGFC monoclonal antibody | Feline |
| GM-Tg-cang-T59510-Ab-1/ GM-Tg-cang-T59510-Ab-2 | Anti-Canine PDGFC monoclonal antibody | Canine |
| GM-Tg-bovg-T59510-Ab-1/ GM-Tg-bovg-T59510-Ab-2 | Anti-Bovine PDGFC monoclonal antibody | Bovine |
| GM-Tg-equg-T59510-Ab-1/ GM-Tg-equg-T59510-Ab-2 | Anti-Equine PDGFC monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T59510-Ab-1/ GM-Tg-hg-T59510-Ab-2; GM-Tg-rg-T59510-Ab-1/ GM-Tg-rg-T59510-Ab-2; GM-Tg-mg-T59510-Ab-1/ GM-Tg-mg-T59510-Ab-2; GM-Tg-cynog-T59510-Ab-1/ GM-Tg-cynog-T59510-Ab-2; GM-Tg-felg-T59510-Ab-1/ GM-Tg-felg-T59510-Ab-2; GM-Tg-cang-T59510-Ab-1/ GM-Tg-cang-T59510-Ab-2; GM-Tg-bovg-T59510-Ab-1/ GM-Tg-bovg-T59510-Ab-2; GM-Tg-equg-T59510-Ab-1/ GM-Tg-equg-T59510-Ab-2 |
| Products Name | Anti-PDGFC monoclonal antibody |
| Format | mab |
| Target Name | PDGFC |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PDGFC benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species PDGFC/ FALLOTEIN/ SCDGF VLP (virus-like particle) (Products Developing) |
| Cytokine | GM-Tg-g-T59510-Ag-1 | platelet derived growth factor C (PDGFC) protein |
| ORF Viral Vector | pGMLP003564 | human PDGFC Lentivirus plasmid |
| ORF Viral Vector | vGMLP003564 | human PDGFC Lentivirus particle |
| ORF Viral Vector | pGMLPm001632 | mouse Pdgfc Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001632 | mouse Pdgfc Lentivirus particle |
Target information
| Target ID | GM-T59510 |
| Target Name | PDGFC |
| Gene ID | 56034,54635,79429,700236,482666,101088742,613787,100062015 |
| Gene Symbol and Synonyms | 1110064L01Rik,FALLOTEIN,PDGF-C,PDGFC,SCDGF,VEGF-E |
| Uniprot Accession | Q9NRA1,Q9EQX6 |
| Uniprot Entry Name | PDGFC_HUMAN,PDGFC_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000145431 |
| Target Classification | N/A |
The target: PDGFC, gene name: PDGFC, also named as FALLOTEIN, SCDGF. The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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