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Anti-VEGFD/ FIGF/ VEGF-D functional antibody
Anti-VEGFD/ FIGF/ VEGF-D functional antibody for cell culture, ELISA & in-vivo assay
Go to VEGFD/VEGFD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T63803-Ab-1/ GM-Tg-hg-T63803-Ab-2 | Anti-Human VEGFD monoclonal antibody | Human |
| GM-Tg-rg-T63803-Ab-1/ GM-Tg-rg-T63803-Ab-2 | Anti-Rat VEGFD monoclonal antibody | Rat |
| GM-Tg-mg-T63803-Ab-1/ GM-Tg-mg-T63803-Ab-2 | Anti-Mouse VEGFD monoclonal antibody | Mouse |
| GM-Tg-cynog-T63803-Ab-1/ GM-Tg-cynog-T63803-Ab-2 | Anti-Cynomolgus/ Rhesus macaque VEGFD monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T63803-Ab-1/ GM-Tg-felg-T63803-Ab-2 | Anti-Feline VEGFD monoclonal antibody | Feline |
| GM-Tg-cang-T63803-Ab-1/ GM-Tg-cang-T63803-Ab-2 | Anti-Canine VEGFD monoclonal antibody | Canine |
| GM-Tg-bovg-T63803-Ab-1/ GM-Tg-bovg-T63803-Ab-2 | Anti-Bovine VEGFD monoclonal antibody | Bovine |
| GM-Tg-equg-T63803-Ab-1/ GM-Tg-equg-T63803-Ab-2 | Anti-Equine VEGFD monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T63803-Ab-1/ GM-Tg-hg-T63803-Ab-2; GM-Tg-rg-T63803-Ab-1/ GM-Tg-rg-T63803-Ab-2; GM-Tg-mg-T63803-Ab-1/ GM-Tg-mg-T63803-Ab-2; GM-Tg-cynog-T63803-Ab-1/ GM-Tg-cynog-T63803-Ab-2; GM-Tg-felg-T63803-Ab-1/ GM-Tg-felg-T63803-Ab-2; GM-Tg-cang-T63803-Ab-1/ GM-Tg-cang-T63803-Ab-2; GM-Tg-bovg-T63803-Ab-1/ GM-Tg-bovg-T63803-Ab-2; GM-Tg-equg-T63803-Ab-1/ GM-Tg-equg-T63803-Ab-2 |
| Products Name | Anti-VEGFD monoclonal antibody |
| Format | mab |
| Target Name | VEGFD |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-VEGFD benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T63803-Ag-1 | Recombinant multi-species VEGFD/ FIGF/ VEGF-D protein |
| Cytokine | GM-Tg-g-T63803-Ag-1 | c-fos induced growth factor (vascular endothelial growth factor D) (FIGF) protein |
| ORF Viral Vector | pGMLP002231 | human VEGFD Lentivirus plasmid |
| ORF Viral Vector | vGMLP002231 | human VEGFD Lentivirus particle |
| ORF Viral Vector | pGMLPm001100 | mouse Vegfd Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001100 | mouse Vegfd Lentivirus particle |
Target information
| Target ID | GM-T63803 |
| Target Name | VEGFD |
| Gene ID | 2277,14205,360457,712654,491749,493703,286799,100050877 |
| Gene Symbol and Synonyms | FIGF,VEGF-D,VEGFD |
| Uniprot Accession | O43915,O35251 |
| Uniprot Entry Name | VEGFD_HUMAN,VEGFD_RAT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, Cytokine Target |
| Disease | Breast Cancer |
| Gene Ensembl | ENSG00000165197 |
| Target Classification | N/A |
The target: VEGFD, gene name: VEGFD, also named as FIGF, VEGF-D. The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. Read-through transcription has been observed between this locus and the upstream PIR (GeneID 8544) locus. [provided by RefSeq, Feb 2011].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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