Anti-GPR20 monoclonal antibody

Anti-GPR20 antibody for FACS & in-vivo assay

Target products collectionGo to GPR20/GPR20 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T65429-Ab-1/ GM-Tg-hg-T65429-Ab-2Anti-Human GPR20 monoclonal antibodyHuman
GM-Tg-rg-T65429-Ab-1/ GM-Tg-rg-T65429-Ab-2Anti-Rat GPR20 monoclonal antibodyRat
GM-Tg-mg-T65429-Ab-1/ GM-Tg-mg-T65429-Ab-2Anti-Mouse GPR20 monoclonal antibodyMouse
GM-Tg-cynog-T65429-Ab-1/ GM-Tg-cynog-T65429-Ab-2Anti-Cynomolgus/ Rhesus macaque GPR20 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T65429-Ab-1/ GM-Tg-felg-T65429-Ab-2Anti-Feline GPR20 monoclonal antibodyFeline
GM-Tg-cang-T65429-Ab-1/ GM-Tg-cang-T65429-Ab-2Anti-Canine GPR20 monoclonal antibodyCanine
GM-Tg-bovg-T65429-Ab-1/ GM-Tg-bovg-T65429-Ab-2Anti-Bovine GPR20 monoclonal antibodyBovine
GM-Tg-equg-T65429-Ab-1/ GM-Tg-equg-T65429-Ab-2Anti-Equine GPR20 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T65429-Ab-1/ GM-Tg-hg-T65429-Ab-2; GM-Tg-rg-T65429-Ab-1/ GM-Tg-rg-T65429-Ab-2;
GM-Tg-mg-T65429-Ab-1/ GM-Tg-mg-T65429-Ab-2; GM-Tg-cynog-T65429-Ab-1/ GM-Tg-cynog-T65429-Ab-2;
GM-Tg-felg-T65429-Ab-1/ GM-Tg-felg-T65429-Ab-2; GM-Tg-cang-T65429-Ab-1/ GM-Tg-cang-T65429-Ab-2;
GM-Tg-bovg-T65429-Ab-1/ GM-Tg-bovg-T65429-Ab-2; GM-Tg-equg-T65429-Ab-1/ GM-Tg-equg-T65429-Ab-2
Products NameAnti-GPR20 monoclonal antibody
Formatmab
Target NameGPR20
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-GPR20 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GPR20 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP003584human GPR20 Lentivirus plasmid
    ORF Viral VectorvGMLP003584human GPR20 Lentivirus particle
    ORF Viral VectorpGMLPm003864mouse Gpr20 Lentivirus plasmid
    ORF Viral VectorvGMLPm003864mouse Gpr20 Lentivirus particle


    Target information

    Target IDGM-T65429
    Target NameGPR20
    Gene ID2843,239530,60667,693582,482061,109496266,515695,100069651
    Gene Symbol and SynonymsA430106B11Rik,Gpcr5-1,GPR20,P2Y4
    Uniprot AccessionQ99678
    Uniprot Entry NameGPR20_HUMAN
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000204882
    Target ClassificationGPCR

    The target: GPR20, gene name: GPR20, also named as . Enables G protein-coupled receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway. Located in cytosol and plasma membrane. Is integral component of plasma membrane. Part of receptor complex..



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.