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Anti-NR4A2 monoclonal antibody
Pre-made anti-NR4A2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to NR4A2/NR4A2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T67163-Ab-1/ GM-Tg-hg-T67163-Ab-2 | Anti-Human NR4A2 monoclonal antibody | Human |
| GM-Tg-rg-T67163-Ab-1/ GM-Tg-rg-T67163-Ab-2 | Anti-Rat NR4A2 monoclonal antibody | Rat |
| GM-Tg-mg-T67163-Ab-1/ GM-Tg-mg-T67163-Ab-2 | Anti-Mouse NR4A2 monoclonal antibody | Mouse |
| GM-Tg-cynog-T67163-Ab-1/ GM-Tg-cynog-T67163-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NR4A2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T67163-Ab-1/ GM-Tg-felg-T67163-Ab-2 | Anti-Feline NR4A2 monoclonal antibody | Feline |
| GM-Tg-cang-T67163-Ab-1/ GM-Tg-cang-T67163-Ab-2 | Anti-Canine NR4A2 monoclonal antibody | Canine |
| GM-Tg-bovg-T67163-Ab-1/ GM-Tg-bovg-T67163-Ab-2 | Anti-Bovine NR4A2 monoclonal antibody | Bovine |
| GM-Tg-equg-T67163-Ab-1/ GM-Tg-equg-T67163-Ab-2 | Anti-Equine NR4A2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T67163-Ab-1/ GM-Tg-hg-T67163-Ab-2; GM-Tg-rg-T67163-Ab-1/ GM-Tg-rg-T67163-Ab-2; GM-Tg-mg-T67163-Ab-1/ GM-Tg-mg-T67163-Ab-2; GM-Tg-cynog-T67163-Ab-1/ GM-Tg-cynog-T67163-Ab-2; GM-Tg-felg-T67163-Ab-1/ GM-Tg-felg-T67163-Ab-2; GM-Tg-cang-T67163-Ab-1/ GM-Tg-cang-T67163-Ab-2; GM-Tg-bovg-T67163-Ab-1/ GM-Tg-bovg-T67163-Ab-2; GM-Tg-equg-T67163-Ab-1/ GM-Tg-equg-T67163-Ab-2 |
| Products Name | Anti-NR4A2 monoclonal antibody |
| Format | mab |
| Target Name | NR4A2 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-NR4A2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T67163-Ag-1 | Recombinant multi-species NR4A2/ HZF-3/ NOT protein |
| ORF Viral Vector | vGMAD000193 | human NR4A2 Adenovirus particle |
| ORF Viral Vector | pGMAD000193 | human NR4A2 Adenovirus plasmid |
| ORF Viral Vector | pGMLPm003037 | mouse Nr4a2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003037 | mouse Nr4a2 Lentivirus particle |
Target information
| Target ID | GM-T67163 |
| Target Name | NR4A2 |
| Gene ID | 4929,18227,54278,697077,478754,101089537,540245,100050666 |
| Gene Symbol and Synonyms | HZF-3,IDLDP,NOT,NR4A2,NURR1,RNR-1,RNR1,TINOR,TINUR |
| Uniprot Accession | P43354,Q07917,Q08E53 |
| Uniprot Entry Name | NR4A2_HUMAN,NR4A2_RAT,NR4A2_BOVIN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000153234 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: NR4A2, gene name: NR4A2, also named as HZF-3, NOT, NURR1, RNR1, TINUR. This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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