Anti-KMT5C monoclonal antibody

Pre-made anti-KMT5C monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to KMT5C/KMT5C products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T68490-Ab-1/ GM-Tg-hg-T68490-Ab-2Anti-Human KMT5C monoclonal antibodyHuman
GM-Tg-rg-T68490-Ab-1/ GM-Tg-rg-T68490-Ab-2Anti-Rat KMT5C monoclonal antibodyRat
GM-Tg-mg-T68490-Ab-1/ GM-Tg-mg-T68490-Ab-2Anti-Mouse KMT5C monoclonal antibodyMouse
GM-Tg-cynog-T68490-Ab-1/ GM-Tg-cynog-T68490-Ab-2Anti-Cynomolgus/ Rhesus macaque KMT5C monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T68490-Ab-1/ GM-Tg-felg-T68490-Ab-2Anti-Feline KMT5C monoclonal antibodyFeline
GM-Tg-cang-T68490-Ab-1/ GM-Tg-cang-T68490-Ab-2Anti-Canine KMT5C monoclonal antibodyCanine
GM-Tg-bovg-T68490-Ab-1/ GM-Tg-bovg-T68490-Ab-2Anti-Bovine KMT5C monoclonal antibodyBovine
GM-Tg-equg-T68490-Ab-1/ GM-Tg-equg-T68490-Ab-2Anti-Equine KMT5C monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T68490-Ab-1/ GM-Tg-hg-T68490-Ab-2; GM-Tg-rg-T68490-Ab-1/ GM-Tg-rg-T68490-Ab-2;
GM-Tg-mg-T68490-Ab-1/ GM-Tg-mg-T68490-Ab-2; GM-Tg-cynog-T68490-Ab-1/ GM-Tg-cynog-T68490-Ab-2;
GM-Tg-felg-T68490-Ab-1/ GM-Tg-felg-T68490-Ab-2; GM-Tg-cang-T68490-Ab-1/ GM-Tg-cang-T68490-Ab-2;
GM-Tg-bovg-T68490-Ab-1/ GM-Tg-bovg-T68490-Ab-2; GM-Tg-equg-T68490-Ab-1/ GM-Tg-equg-T68490-Ab-2
Products NameAnti-KMT5C monoclonal antibody
Formatmab
Target NameKMT5C
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-KMT5C monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T68490-Ag-1Recombinant multi-species KMT5C/ SUV420H2/ Suv4-20h2 protein


    Target information

    Target IDGM-T68490
    Target NameKMT5C
    Gene ID84787,232811,308345,699963,484295,101091322,519777,100055743
    Gene Symbol and SynonymsKMT5C,Suv4-20h2,SUV420H2
    Uniprot AccessionQ86Y97,P0C2N6
    Uniprot Entry NameKMT5C_HUMAN,KMT5C_RAT
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000133247
    Target ClassificationN/A

    The target: KMT5C, gene name: KMT5C, also named as SUV420H2, Suv4-20h2. SUV420H2 and the related enzyme SUV420H1 (MIM 610881) function as histone methyltransferases that specifically trimethylate nucleosomal histone H4 (see MIM 602822) on lysine-20 (K20) (Schotta et al., 2004 [PubMed 15145825]).[supplied by OMIM, Dec 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.