Anti-WEE1 monoclonal antibody

Pre-made anti-WEE1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to WEE1/WEE1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T69991-Ab-1/ GM-Tg-hg-T69991-Ab-2Anti-Human WEE1 monoclonal antibodyHuman
GM-Tg-rg-T69991-Ab-1/ GM-Tg-rg-T69991-Ab-2Anti-Rat WEE1 monoclonal antibodyRat
GM-Tg-mg-T69991-Ab-1/ GM-Tg-mg-T69991-Ab-2Anti-Mouse WEE1 monoclonal antibodyMouse
GM-Tg-cynog-T69991-Ab-1/ GM-Tg-cynog-T69991-Ab-2Anti-Cynomolgus/ Rhesus macaque WEE1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T69991-Ab-1/ GM-Tg-felg-T69991-Ab-2Anti-Feline WEE1 monoclonal antibodyFeline
GM-Tg-cang-T69991-Ab-1/ GM-Tg-cang-T69991-Ab-2Anti-Canine WEE1 monoclonal antibodyCanine
GM-Tg-bovg-T69991-Ab-1/ GM-Tg-bovg-T69991-Ab-2Anti-Bovine WEE1 monoclonal antibodyBovine
GM-Tg-equg-T69991-Ab-1/ GM-Tg-equg-T69991-Ab-2Anti-Equine WEE1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T69991-Ab-1/ GM-Tg-hg-T69991-Ab-2; GM-Tg-rg-T69991-Ab-1/ GM-Tg-rg-T69991-Ab-2;
GM-Tg-mg-T69991-Ab-1/ GM-Tg-mg-T69991-Ab-2; GM-Tg-cynog-T69991-Ab-1/ GM-Tg-cynog-T69991-Ab-2;
GM-Tg-felg-T69991-Ab-1/ GM-Tg-felg-T69991-Ab-2; GM-Tg-cang-T69991-Ab-1/ GM-Tg-cang-T69991-Ab-2;
GM-Tg-bovg-T69991-Ab-1/ GM-Tg-bovg-T69991-Ab-2; GM-Tg-equg-T69991-Ab-1/ GM-Tg-equg-T69991-Ab-2
Products NameAnti-WEE1 monoclonal antibody
Formatmab
Target NameWEE1
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-WEE1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T69991-Ag-1Recombinant multi-species WEE1/ WEE1Ahu protein


    Target information

    Target IDGM-T69991
    Target NameWEE1
    Gene ID7465,22390,308937,703760,476847,101091897,540322,100071182
    Gene Symbol and SynonymsWEE1,WEE1A,WEE1hu
    Uniprot AccessionP30291,Q63802
    Uniprot Entry NameWEE1_HUMAN,WEE1_RAT
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseCancer
    Gene EnsemblENSG00000166483
    Target ClassificationKinase, Tumor-associated antigen (TAA)

    The target: WEE1, gene name: WEE1, also named as WEE1Ahu, WEE1. This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.