Anti-USP10 monoclonal antibody

Pre-made anti-USP10 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to USP10/USP10 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T73582-Ab-1/ GM-Tg-hg-T73582-Ab-2Anti-Human USP10 monoclonal antibodyHuman
GM-Tg-rg-T73582-Ab-1/ GM-Tg-rg-T73582-Ab-2Anti-Rat USP10 monoclonal antibodyRat
GM-Tg-mg-T73582-Ab-1/ GM-Tg-mg-T73582-Ab-2Anti-Mouse USP10 monoclonal antibodyMouse
GM-Tg-cynog-T73582-Ab-1/ GM-Tg-cynog-T73582-Ab-2Anti-Cynomolgus/ Rhesus macaque USP10 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T73582-Ab-1/ GM-Tg-felg-T73582-Ab-2Anti-Feline USP10 monoclonal antibodyFeline
GM-Tg-cang-T73582-Ab-1/ GM-Tg-cang-T73582-Ab-2Anti-Canine USP10 monoclonal antibodyCanine
GM-Tg-bovg-T73582-Ab-1/ GM-Tg-bovg-T73582-Ab-2Anti-Bovine USP10 monoclonal antibodyBovine
GM-Tg-equg-T73582-Ab-1/ GM-Tg-equg-T73582-Ab-2Anti-Equine USP10 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T73582-Ab-1/ GM-Tg-hg-T73582-Ab-2; GM-Tg-rg-T73582-Ab-1/ GM-Tg-rg-T73582-Ab-2;
GM-Tg-mg-T73582-Ab-1/ GM-Tg-mg-T73582-Ab-2; GM-Tg-cynog-T73582-Ab-1/ GM-Tg-cynog-T73582-Ab-2;
GM-Tg-felg-T73582-Ab-1/ GM-Tg-felg-T73582-Ab-2; GM-Tg-cang-T73582-Ab-1/ GM-Tg-cang-T73582-Ab-2;
GM-Tg-bovg-T73582-Ab-1/ GM-Tg-bovg-T73582-Ab-2; GM-Tg-equg-T73582-Ab-1/ GM-Tg-equg-T73582-Ab-2
Products NameAnti-USP10 monoclonal antibody
Formatmab
Target NameUSP10
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-USP10 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T73582-Ag-1Recombinant multi-species UBP10/ USP10/ UBPO protein
    ORF Viral VectorpGMAD000600Norway rat Usp10 Adenovirus plasmid
    ORF Viral VectorpGMAAV000239house mouse Usp10 AAV plasmid
    ORF Viral VectorvGMAD000600Norway rat Usp10 Adenovirus particle
    ORF Viral VectorvGMAAV000239house mouse Usp10 AAV particle


    Target information

    Target IDGM-T73582
    Target NameUSP10
    Gene ID9100,22224,307905,718471,479625,101089411,510164,100070208
    Gene Symbol and Synonyms2610014N07Rik,mKIAA0190,UBPO,Uchrp,USP10
    Uniprot AccessionQ14694,Q3KR59,A5PJS6
    Uniprot Entry NameUBP10_HUMAN,UBP10_RAT,UBP10_BOVIN
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000103194
    Target ClassificationN/A

    The target: USP10, gene name: USP10, also named as UBPO. Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and others not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2013].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.