Anti-USP10 monoclonal antibody
Pre-made anti-USP10 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T73582-Ab-1/ GM-Tg-hg-T73582-Ab-2 | Anti-Human USP10 monoclonal antibody | Human |
GM-Tg-rg-T73582-Ab-1/ GM-Tg-rg-T73582-Ab-2 | Anti-Rat USP10 monoclonal antibody | Rat |
GM-Tg-mg-T73582-Ab-1/ GM-Tg-mg-T73582-Ab-2 | Anti-Mouse USP10 monoclonal antibody | Mouse |
GM-Tg-cynog-T73582-Ab-1/ GM-Tg-cynog-T73582-Ab-2 | Anti-Cynomolgus/ Rhesus macaque USP10 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T73582-Ab-1/ GM-Tg-felg-T73582-Ab-2 | Anti-Feline USP10 monoclonal antibody | Feline |
GM-Tg-cang-T73582-Ab-1/ GM-Tg-cang-T73582-Ab-2 | Anti-Canine USP10 monoclonal antibody | Canine |
GM-Tg-bovg-T73582-Ab-1/ GM-Tg-bovg-T73582-Ab-2 | Anti-Bovine USP10 monoclonal antibody | Bovine |
GM-Tg-equg-T73582-Ab-1/ GM-Tg-equg-T73582-Ab-2 | Anti-Equine USP10 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-T73582-Ab-1/ GM-Tg-hg-T73582-Ab-2; GM-Tg-rg-T73582-Ab-1/ GM-Tg-rg-T73582-Ab-2; GM-Tg-mg-T73582-Ab-1/ GM-Tg-mg-T73582-Ab-2; GM-Tg-cynog-T73582-Ab-1/ GM-Tg-cynog-T73582-Ab-2; GM-Tg-felg-T73582-Ab-1/ GM-Tg-felg-T73582-Ab-2; GM-Tg-cang-T73582-Ab-1/ GM-Tg-cang-T73582-Ab-2; GM-Tg-bovg-T73582-Ab-1/ GM-Tg-bovg-T73582-Ab-2; GM-Tg-equg-T73582-Ab-1/ GM-Tg-equg-T73582-Ab-2 |
Products Name | Anti-USP10 monoclonal antibody |
Format | mab |
Target Name | USP10 |
Protein Sub-location | Introcelluar Protein |
Category of antibody | Therapeutics Target antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-USP10 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-T73582-Ag-1 | Recombinant multi-species UBP10/ USP10/ UBPO protein |
ORF Viral Vector | pGMAD000600 | Norway rat Usp10 Adenovirus plasmid |
ORF Viral Vector | pGMAAV000239 | house mouse Usp10 AAV plasmid |
ORF Viral Vector | vGMAD000600 | Norway rat Usp10 Adenovirus particle |
ORF Viral Vector | vGMAAV000239 | house mouse Usp10 AAV particle |
Target information
Target ID | GM-T73582 |
Target Name | USP10 |
Gene ID | 9100,22224,307905,718471,479625,101089411,510164,100070208 |
Gene Symbol and Synonyms | 2610014N07Rik,mKIAA0190,UBPO,Uchrp,USP10 |
Uniprot Accession | Q14694,Q3KR59,A5PJS6 |
Uniprot Entry Name | UBP10_HUMAN,UBP10_RAT,UBP10_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | N/A |
Gene Ensembl | ENSG00000103194 |
Target Classification | N/A |
The target: USP10, gene name: USP10, also named as UBPO. Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and others not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.