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Anti-NQO2 monoclonal antibody
Pre-made anti-NQO2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to NQO2/NQO2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T75498-Ab-1/ GM-Tg-hg-T75498-Ab-2 | Anti-Human NQO2 monoclonal antibody | Human |
| GM-Tg-rg-T75498-Ab-1/ GM-Tg-rg-T75498-Ab-2 | Anti-Rat NQO2 monoclonal antibody | Rat |
| GM-Tg-mg-T75498-Ab-1/ GM-Tg-mg-T75498-Ab-2 | Anti-Mouse NQO2 monoclonal antibody | Mouse |
| GM-Tg-cynog-T75498-Ab-1/ GM-Tg-cynog-T75498-Ab-2 | Anti-Cynomolgus/ Rhesus macaque NQO2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T75498-Ab-1/ GM-Tg-felg-T75498-Ab-2 | Anti-Feline NQO2 monoclonal antibody | Feline |
| GM-Tg-cang-T75498-Ab-1/ GM-Tg-cang-T75498-Ab-2 | Anti-Canine NQO2 monoclonal antibody | Canine |
| GM-Tg-bovg-T75498-Ab-1/ GM-Tg-bovg-T75498-Ab-2 | Anti-Bovine NQO2 monoclonal antibody | Bovine |
| GM-Tg-equg-T75498-Ab-1/ GM-Tg-equg-T75498-Ab-2 | Anti-Equine NQO2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T75498-Ab-1/ GM-Tg-hg-T75498-Ab-2; GM-Tg-rg-T75498-Ab-1/ GM-Tg-rg-T75498-Ab-2; GM-Tg-mg-T75498-Ab-1/ GM-Tg-mg-T75498-Ab-2; GM-Tg-cynog-T75498-Ab-1/ GM-Tg-cynog-T75498-Ab-2; GM-Tg-felg-T75498-Ab-1/ GM-Tg-felg-T75498-Ab-2; GM-Tg-cang-T75498-Ab-1/ GM-Tg-cang-T75498-Ab-2; GM-Tg-bovg-T75498-Ab-1/ GM-Tg-bovg-T75498-Ab-2; GM-Tg-equg-T75498-Ab-1/ GM-Tg-equg-T75498-Ab-2 |
| Products Name | Anti-NQO2 monoclonal antibody |
| Format | mab |
| Target Name | NQO2 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-NQO2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T75498-Ag-1 | Recombinant multi-species NQO2/ DHQV/ DIA6 protein |
| ORF Viral Vector | vGMLP003468 | human NQO2 Lentivirus particle |
| ORF Viral Vector | pGMLP004023 | human NQO2 Lentivirus plasmid |
| ORF Viral Vector | vGMLP004023 | human NQO2 Lentivirus particle |
| ORF Viral Vector | pGMLP003468 | human NQO2 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000422 | mouse Nqo2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000422 | mouse Nqo2 Lentivirus particle |
Target information
| Target ID | GM-T75498 |
| Target Name | NQO2 |
| Gene ID | 4835,18105,291084,707675,606932,101085630,508566,100057868 |
| Gene Symbol and Synonyms | DHQV,DIA6,NMO2,NMOR2,NQO2,Ox2,QR2 |
| Uniprot Accession | P16083,Q6AY80 |
| Uniprot Entry Name | NQO2_HUMAN,NQO2_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000124588 |
| Target Classification | N/A |
The target: NQO2, gene name: NQO2, also named as DHQV, DIA6, NMOR2, QR2. This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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