Anti-MT-ND3 monoclonal antibody

Pre-made anti-MT-ND3 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to MT-ND3/MT-ND3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T77195-Ab-1/ GM-Tg-hg-T77195-Ab-2Anti-Human MT-ND3 monoclonal antibodyHuman
GM-Tg-rg-T77195-Ab-1/ GM-Tg-rg-T77195-Ab-2Anti-Rat MT-ND3 monoclonal antibodyRat
GM-Tg-mg-T77195-Ab-1/ GM-Tg-mg-T77195-Ab-2Anti-Mouse MT-ND3 monoclonal antibodyMouse
GM-Tg-cynog-T77195-Ab-1/ GM-Tg-cynog-T77195-Ab-2Anti-Cynomolgus/ Rhesus macaque MT-ND3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T77195-Ab-1/ GM-Tg-felg-T77195-Ab-2Anti-Feline MT-ND3 monoclonal antibodyFeline
GM-Tg-cang-T77195-Ab-1/ GM-Tg-cang-T77195-Ab-2Anti-Canine MT-ND3 monoclonal antibodyCanine
GM-Tg-bovg-T77195-Ab-1/ GM-Tg-bovg-T77195-Ab-2Anti-Bovine MT-ND3 monoclonal antibodyBovine
GM-Tg-equg-T77195-Ab-1/ GM-Tg-equg-T77195-Ab-2Anti-Equine MT-ND3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T77195-Ab-1/ GM-Tg-hg-T77195-Ab-2; GM-Tg-rg-T77195-Ab-1/ GM-Tg-rg-T77195-Ab-2;
GM-Tg-mg-T77195-Ab-1/ GM-Tg-mg-T77195-Ab-2; GM-Tg-cynog-T77195-Ab-1/ GM-Tg-cynog-T77195-Ab-2;
GM-Tg-felg-T77195-Ab-1/ GM-Tg-felg-T77195-Ab-2; GM-Tg-cang-T77195-Ab-1/ GM-Tg-cang-T77195-Ab-2;
GM-Tg-bovg-T77195-Ab-1/ GM-Tg-bovg-T77195-Ab-2; GM-Tg-equg-T77195-Ab-1/ GM-Tg-equg-T77195-Ab-2
Products NameAnti-MT-ND3 monoclonal antibody
Formatmab
Target NameMT-ND3
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-MT-ND3 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T77195-Ag-1Recombinant multi-species NU3M/ MT-ND3/ MTND3 protein


    Target information

    Target IDGM-T77195
    Target NameMT-ND3
    Gene ID4537
    Gene Symbol and SynonymsMT-ND3,MTND3
    Uniprot AccessionP03897
    Uniprot Entry NameNU3M_HUMAN
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000198840
    Target ClassificationN/A

    The target: MT-ND3, gene name: MT-ND3, also named as MTND3, ND3. Enables NADH dehydrogenase (ubiquinone) activity. Involved in mitochondrial electron transport, NADH to ubiquinone. Part of mitochondrial respiratory chain complex I. Implicated in Leber hereditary optic neuropathy; Leigh disease; and Parkinson's disease. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.