Anti-PDE2A monoclonal antibody

Pre-made anti-PDE2A monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to PDE2A/PDE2A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T77400-Ab-1/ GM-Tg-hg-T77400-Ab-2Anti-Human PDE2A monoclonal antibodyHuman
GM-Tg-rg-T77400-Ab-1/ GM-Tg-rg-T77400-Ab-2Anti-Rat PDE2A monoclonal antibodyRat
GM-Tg-mg-T77400-Ab-1/ GM-Tg-mg-T77400-Ab-2Anti-Mouse PDE2A monoclonal antibodyMouse
GM-Tg-cynog-T77400-Ab-1/ GM-Tg-cynog-T77400-Ab-2Anti-Cynomolgus/ Rhesus macaque PDE2A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T77400-Ab-1/ GM-Tg-felg-T77400-Ab-2Anti-Feline PDE2A monoclonal antibodyFeline
GM-Tg-cang-T77400-Ab-1/ GM-Tg-cang-T77400-Ab-2Anti-Canine PDE2A monoclonal antibodyCanine
GM-Tg-bovg-T77400-Ab-1/ GM-Tg-bovg-T77400-Ab-2Anti-Bovine PDE2A monoclonal antibodyBovine
GM-Tg-equg-T77400-Ab-1/ GM-Tg-equg-T77400-Ab-2Anti-Equine PDE2A monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T77400-Ab-1/ GM-Tg-hg-T77400-Ab-2; GM-Tg-rg-T77400-Ab-1/ GM-Tg-rg-T77400-Ab-2;
GM-Tg-mg-T77400-Ab-1/ GM-Tg-mg-T77400-Ab-2; GM-Tg-cynog-T77400-Ab-1/ GM-Tg-cynog-T77400-Ab-2;
GM-Tg-felg-T77400-Ab-1/ GM-Tg-felg-T77400-Ab-2; GM-Tg-cang-T77400-Ab-1/ GM-Tg-cang-T77400-Ab-2;
GM-Tg-bovg-T77400-Ab-1/ GM-Tg-bovg-T77400-Ab-2; GM-Tg-equg-T77400-Ab-1/ GM-Tg-equg-T77400-Ab-2
Products NameAnti-PDE2A monoclonal antibody
Formatmab
Target NamePDE2A
Protein Sub-locationIntrocelluar Protein
Category of antibodyTherapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-PDE2A monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


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    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-T77400-Ag-1Recombinant multi-species PDE2A/ CGS-PDE1/ PED2A4 protein


    Target information

    Target IDGM-T77400
    Target NamePDE2A
    Gene ID5138,207728,81743,718479,609574,101083366,281971,100052619
    Gene Symbol and SynonymsCGS-PDE,cGSPDE,IDDPADS,Pde2,PDE2A,PDE2A1,Pde2a2,PED2A4
    Uniprot AccessionO00408,Q01062,P14099
    Uniprot Entry NamePDE2A_HUMAN,PDE2A_RAT,PDE2A_BOVIN
    Protein Sub-locationIntrocelluar Protein
    CategoryTherapeutics Target
    DiseaseIgA glomerulonephritis
    Gene EnsemblENSG00000186642
    Target ClassificationN/A

    The target: PDE2A, gene name: PDE2A, also named as CGS-PDE1, PED2A4, cGSPDE, PDE2A. Enables several functions, including 3',5'-cyclic-nucleotide phosphodiesterase activity; anion binding activity; and metal ion binding activity. Involved in several processes, including cellular response to organic cyclic compound; cyclic-nucleotide-mediated signaling; and regulation of vascular permeability. Located in several cellular components, including cytosol; mitochondrial membrane; and perinuclear region of cytoplasm. Colocalizes with plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.