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Anti-IFNG/ IFG/ IFI functional antibody
Anti-IFNG/ IFG/ IFI functional antibody for cell culture, ELISA & in-vivo assay
Go to IFNG/IFNG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T77664-Ab-1/ GM-Tg-hg-T77664-Ab-2 | Anti-Human IFNG monoclonal antibody | Human |
| GM-Tg-rg-T77664-Ab-1/ GM-Tg-rg-T77664-Ab-2 | Anti-Rat IFNG monoclonal antibody | Rat |
| GM-Tg-mg-T77664-Ab-1/ GM-Tg-mg-T77664-Ab-2 | Anti-Mouse IFNG monoclonal antibody | Mouse |
| GM-Tg-cynog-T77664-Ab-1/ GM-Tg-cynog-T77664-Ab-2 | Anti-Cynomolgus/ Rhesus macaque IFNG monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T77664-Ab-1/ GM-Tg-felg-T77664-Ab-2 | Anti-Feline IFNG monoclonal antibody | Feline |
| GM-Tg-cang-T77664-Ab-1/ GM-Tg-cang-T77664-Ab-2 | Anti-Canine IFNG monoclonal antibody | Canine |
| GM-Tg-bovg-T77664-Ab-1/ GM-Tg-bovg-T77664-Ab-2 | Anti-Bovine IFNG monoclonal antibody | Bovine |
| GM-Tg-equg-T77664-Ab-1/ GM-Tg-equg-T77664-Ab-2 | Anti-Equine IFNG monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T77664-Ab-1/ GM-Tg-hg-T77664-Ab-2; GM-Tg-rg-T77664-Ab-1/ GM-Tg-rg-T77664-Ab-2; GM-Tg-mg-T77664-Ab-1/ GM-Tg-mg-T77664-Ab-2; GM-Tg-cynog-T77664-Ab-1/ GM-Tg-cynog-T77664-Ab-2; GM-Tg-felg-T77664-Ab-1/ GM-Tg-felg-T77664-Ab-2; GM-Tg-cang-T77664-Ab-1/ GM-Tg-cang-T77664-Ab-2; GM-Tg-bovg-T77664-Ab-1/ GM-Tg-bovg-T77664-Ab-2; GM-Tg-equg-T77664-Ab-1/ GM-Tg-equg-T77664-Ab-2 |
| Products Name | Anti-IFNG monoclonal antibody |
| Format | mab |
| Target Name | IFNG |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-IFNG benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Biosimilar | GMP-Bios-ab-175 | Pre-Made Emapalumab biosimilar, Whole mAb, Anti-IFNG Antibody: Anti-IFG/IFI/IMD69 therapeutic antibody |
| Biosimilar | GMP-Bios-ab-219 | Pre-Made Fontolizumab biosimilar, Whole mAb, Anti-IFNG Antibody: Anti-IFG/IFI/IMD69 therapeutic antibody |
| Target Antigen | GM-Tg-g-T77664-Ag-1 | Recombinant multi-species IFNG/ IFG/ IFI protein |
| Cytokine | GM-Tg-g-T77664-Ag-1 | interferon, gamma (IFNG) protein |
| ORF Viral Vector | vGMAD000575 | human IFNG Adenovirus particle |
| ORF Viral Vector | pGMAP000297 | Human IFNG Adenovirus plasmid |
| ORF Viral Vector | vGMLP000461 | human IFNG Lentivirus particle |
| ORF Viral Vector | vGMAP000297 | Human IFNG Adenovirus particle |
| ORF Viral Vector | pGMAD000575 | human IFNG Adenovirus plasmid |
| ORF Viral Vector | pGMLP000461 | human IFNG Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000110 | mouse Ifng Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000110 | mouse Ifng Lentivirus particle |
Target information
| Target ID | GM-T77664 |
| Target Name | IFNG |
| Gene ID | 3458,15978,25712,574282,403801,493965,281237,100034181 |
| Gene Symbol and Synonyms | If2f,IFG,IFI,IFN-g,IFN-gamma,IFNG,IFNG2,IMD69 |
| Uniprot Accession | P01579,P01581,P63310,P42161,P46402,P07353,P42160 |
| Uniprot Entry Name | IFNG_HUMAN,IFNG_MACMU,IFNG_RAT,IFNG_FELCA,IFNG_CANLF,IFNG_BOVIN,IFNG_HORSE |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | Therapeutics Target, Diagnostics Biomarker, Immuno-oncology Target, INN Index, Cytokine Target |
| Disease | Breast Cancer |
| Gene Ensembl | ENSG00000111537 |
| Target Classification | Checkpoint-Immuno Oncology |
The target: IFNG, gene name: IFNG, also named as IFG, IFI. This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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