Anti-CSNK2A2 monoclonal antibody
Pre-made anti-CSNK2A2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T80526-Ab-1/ GM-Tg-hg-T80526-Ab-2 | Anti-Human CSNK2A2 monoclonal antibody | Human |
GM-Tg-rg-T80526-Ab-1/ GM-Tg-rg-T80526-Ab-2 | Anti-Rat CSNK2A2 monoclonal antibody | Rat |
GM-Tg-mg-T80526-Ab-1/ GM-Tg-mg-T80526-Ab-2 | Anti-Mouse CSNK2A2 monoclonal antibody | Mouse |
GM-Tg-cynog-T80526-Ab-1/ GM-Tg-cynog-T80526-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CSNK2A2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T80526-Ab-1/ GM-Tg-felg-T80526-Ab-2 | Anti-Feline CSNK2A2 monoclonal antibody | Feline |
GM-Tg-cang-T80526-Ab-1/ GM-Tg-cang-T80526-Ab-2 | Anti-Canine CSNK2A2 monoclonal antibody | Canine |
GM-Tg-bovg-T80526-Ab-1/ GM-Tg-bovg-T80526-Ab-2 | Anti-Bovine CSNK2A2 monoclonal antibody | Bovine |
GM-Tg-equg-T80526-Ab-1/ GM-Tg-equg-T80526-Ab-2 | Anti-Equine CSNK2A2 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-T80526-Ab-1/ GM-Tg-hg-T80526-Ab-2; GM-Tg-rg-T80526-Ab-1/ GM-Tg-rg-T80526-Ab-2; GM-Tg-mg-T80526-Ab-1/ GM-Tg-mg-T80526-Ab-2; GM-Tg-cynog-T80526-Ab-1/ GM-Tg-cynog-T80526-Ab-2; GM-Tg-felg-T80526-Ab-1/ GM-Tg-felg-T80526-Ab-2; GM-Tg-cang-T80526-Ab-1/ GM-Tg-cang-T80526-Ab-2; GM-Tg-bovg-T80526-Ab-1/ GM-Tg-bovg-T80526-Ab-2; GM-Tg-equg-T80526-Ab-1/ GM-Tg-equg-T80526-Ab-2 |
Products Name | Anti-CSNK2A2 monoclonal antibody |
Format | mab |
Target Name | CSNK2A2 |
Protein Sub-location | Introcelluar Protein |
Category of antibody | Therapeutics Target antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-CSNK2A2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | GM-Tg-g-T80526-Ag-1 | Recombinant multi-species CSK22/ CSNK2A2/ CK2A2 protein |
ORF Viral Vector | vGMAD000128 | human CSNK2A2 Adenovirus particle |
ORF Viral Vector | pGMLP004104 | human CSNK2A2 Lentivirus plasmid |
ORF Viral Vector | vGMLPm004017 | mouse CSNK2A2 Lentivirus particle |
ORF Viral Vector | vGMLP004104 | human CSNK2A2 Lentivirus particle |
ORF Viral Vector | pGMAD000128 | human CSNK2A2 Adenovirus plasmid |
ORF Viral Vector | pGMLPm004017 | mouse CSNK2A2 Lentivirus plasmid |
ORF Viral Vector | pGMLPm005299 | mouse Csnk2a2 Lentivirus plasmid |
ORF Viral Vector | vGMLPm005299 | mouse Csnk2a2 Lentivirus particle |
Target information
Target ID | GM-T80526 |
Target Name | CSNK2A2 |
Gene ID | 1459,13000,307641,712455,478108,101093065,282420,100063080 |
Gene Symbol and Synonyms | 1110035J23Rik,CK2,CK2A2,CK2alpha',CSNK2A1,CSNK2A2 |
Uniprot Accession | P19784,P20427 |
Uniprot Entry Name | CSK22_HUMAN,CSK22_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | N/A |
Gene Ensembl | ENSG00000070770 |
Target Classification | Kinase |
The target: CSNK2A2, gene name: CSNK2A2, also named as CK2A2, CK2alpha', CSNK2A1. This gene encodes the alpha', or alpha 2, catalytic subunit of the protein kinase enzyme, casein kinase 2 (CK2). Casein kinase 2 is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythms. This heterotetrameric kinase includes two catalytic subunits, either alpha or alpha', and two regulatory beta subunits. The closely related gene paralog encoding the alpha, or alpha 1 subunit (CSNK2A1, Gene ID: 1457) is found on chromosome 20. An intronic variant in this gene (alpha 2) may be associated with leukocyte telomere length in a South Asian population. A related transcribed pseudogene is found on chromosome 11. [provided by RefSeq, Aug 2017].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.