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Anti-Bach1 monoclonal antibody
Pre-made anti-Bach1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to Bach1/BACH1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T80886-Ab-1/ GM-Tg-hg-T80886-Ab-2 | Anti-Human Bach1/BACH1 monoclonal antibody | Human |
| GM-Tg-rg-T80886-Ab-1/ GM-Tg-rg-T80886-Ab-2 | Anti-Rat Bach1/BACH1 monoclonal antibody | Rat |
| GM-Tg-mg-T80886-Ab-1/ GM-Tg-mg-T80886-Ab-2 | Anti-Mouse Bach1/BACH1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T80886-Ab-1/ GM-Tg-cynog-T80886-Ab-2 | Anti-Cynomolgus/ Rhesus macaque Bach1/BACH1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T80886-Ab-1/ GM-Tg-felg-T80886-Ab-2 | Anti-Feline Bach1/BACH1 monoclonal antibody | Feline |
| GM-Tg-cang-T80886-Ab-1/ GM-Tg-cang-T80886-Ab-2 | Anti-Canine Bach1/BACH1 monoclonal antibody | Canine |
| GM-Tg-bovg-T80886-Ab-1/ GM-Tg-bovg-T80886-Ab-2 | Anti-Bovine Bach1/BACH1 monoclonal antibody | Bovine |
| GM-Tg-equg-T80886-Ab-1/ GM-Tg-equg-T80886-Ab-2 | Anti-Equine Bach1/BACH1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T80886-Ab-1/ GM-Tg-hg-T80886-Ab-2; GM-Tg-rg-T80886-Ab-1/ GM-Tg-rg-T80886-Ab-2; GM-Tg-mg-T80886-Ab-1/ GM-Tg-mg-T80886-Ab-2; GM-Tg-cynog-T80886-Ab-1/ GM-Tg-cynog-T80886-Ab-2; GM-Tg-felg-T80886-Ab-1/ GM-Tg-felg-T80886-Ab-2; GM-Tg-cang-T80886-Ab-1/ GM-Tg-cang-T80886-Ab-2; GM-Tg-bovg-T80886-Ab-1/ GM-Tg-bovg-T80886-Ab-2; GM-Tg-equg-T80886-Ab-1/ GM-Tg-equg-T80886-Ab-2 |
| Products Name | Anti-Bach1/BACH1 monoclonal antibody |
| Format | mab |
| Target Name | Bach1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-Bach1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T80886-Ag-1 | Recombinant multi-species BACH1/ Bach1/ BACH-1 protein |
| ORF Viral Vector | pGMAD000089 | human BACH1 Adenovirus plasmid |
| ORF Viral Vector | vGMAD000089 | human BACH1 Adenovirus particle |
Target information
| Target ID | GM-T80886 |
| Target Name | Bach1 |
| Gene ID | 571,12013,304127,705817,487718,101097412,531350,100053654 |
| Gene Symbol and Synonyms | 6230421P05Rik,BACH-1,BACH1,BTBD24 |
| Uniprot Accession | O14867 |
| Uniprot Entry Name | BACH1_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | Cancer |
| Gene Ensembl | ENSG00000156273 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: Bach1, gene name: BACH1, also named as BACH-1, BTBD24. This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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