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Anti-IKZF2 monoclonal antibody
Pre-made anti-IKZF2 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to IKZF2/IKZF2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T81569-Ab-1/ GM-Tg-hg-T81569-Ab-2 | Anti-Human IKZF2 monoclonal antibody | Human |
| GM-Tg-rg-T81569-Ab-1/ GM-Tg-rg-T81569-Ab-2 | Anti-Rat IKZF2 monoclonal antibody | Rat |
| GM-Tg-mg-T81569-Ab-1/ GM-Tg-mg-T81569-Ab-2 | Anti-Mouse IKZF2 monoclonal antibody | Mouse |
| GM-Tg-cynog-T81569-Ab-1/ GM-Tg-cynog-T81569-Ab-2 | Anti-Cynomolgus/ Rhesus macaque IKZF2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T81569-Ab-1/ GM-Tg-felg-T81569-Ab-2 | Anti-Feline IKZF2 monoclonal antibody | Feline |
| GM-Tg-cang-T81569-Ab-1/ GM-Tg-cang-T81569-Ab-2 | Anti-Canine IKZF2 monoclonal antibody | Canine |
| GM-Tg-bovg-T81569-Ab-1/ GM-Tg-bovg-T81569-Ab-2 | Anti-Bovine IKZF2 monoclonal antibody | Bovine |
| GM-Tg-equg-T81569-Ab-1/ GM-Tg-equg-T81569-Ab-2 | Anti-Equine IKZF2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T81569-Ab-1/ GM-Tg-hg-T81569-Ab-2; GM-Tg-rg-T81569-Ab-1/ GM-Tg-rg-T81569-Ab-2; GM-Tg-mg-T81569-Ab-1/ GM-Tg-mg-T81569-Ab-2; GM-Tg-cynog-T81569-Ab-1/ GM-Tg-cynog-T81569-Ab-2; GM-Tg-felg-T81569-Ab-1/ GM-Tg-felg-T81569-Ab-2; GM-Tg-cang-T81569-Ab-1/ GM-Tg-cang-T81569-Ab-2; GM-Tg-bovg-T81569-Ab-1/ GM-Tg-bovg-T81569-Ab-2; GM-Tg-equg-T81569-Ab-1/ GM-Tg-equg-T81569-Ab-2 |
| Products Name | Anti-IKZF2 monoclonal antibody |
| Format | mab |
| Target Name | IKZF2 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-IKZF2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-T81569-Ag-1 | Recombinant multi-species IKZF2/ ANF1A2/ HELIOS protein |
| ORF Viral Vector | pGMLP003993 | human IKZF2 Lentivirus plasmid |
| ORF Viral Vector | pGMLP003292 | human IKZF2 Lentivirus plasmid |
| ORF Viral Vector | vGMLP003292 | human IKZF2 Lentivirus particle |
| ORF Viral Vector | vGMLP003993 | human IKZF2 Lentivirus particle |
| ORF Viral Vector | pGMLPm003053 | mouse Ikzf2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003053 | mouse Ikzf2 Lentivirus particle |
Target information
| Target ID | GM-T81569 |
| Target Name | IKZF2 |
| Gene ID | 22807,22779,301476,693521,488510,101100826,786795 |
| Gene Symbol and Synonyms | A730095J18Rik,ANF1A2,HELIOS,IKZF2,Zfpn1a2,ZNF1A2,ZNFN1A2 |
| Uniprot Accession | Q9UKS7 |
| Uniprot Entry Name | IKZF2_HUMAN |
| Protein Sub-location | Introcelluar Protein |
| Category | Therapeutics Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000030419 |
| Target Classification | N/A |
The target: IKZF2, gene name: IKZF2, also named as ANF1A2, HELIOS, ZNF1A2, ZNFN1A2. This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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