Anti-OX2G/ CD200/ MOX1 monoclonal antibody
Anti-OX2G/ CD200/ MOX1 antibody for FACS & in-vivo assay
Go to CD200/CD200 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T81695-Ab-1/ GM-Tg-hg-T81695-Ab-2 | Anti-Human CD200 monoclonal antibody | Human |
GM-Tg-rg-T81695-Ab-1/ GM-Tg-rg-T81695-Ab-2 | Anti-Rat CD200 monoclonal antibody | Rat |
GM-Tg-mg-T81695-Ab-1/ GM-Tg-mg-T81695-Ab-2 | Anti-Mouse CD200 monoclonal antibody | Mouse |
GM-Tg-cynog-T81695-Ab-1/ GM-Tg-cynog-T81695-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CD200 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T81695-Ab-1/ GM-Tg-felg-T81695-Ab-2 | Anti-Feline CD200 monoclonal antibody | Feline |
GM-Tg-cang-T81695-Ab-1/ GM-Tg-cang-T81695-Ab-2 | Anti-Canine CD200 monoclonal antibody | Canine |
GM-Tg-bovg-T81695-Ab-1/ GM-Tg-bovg-T81695-Ab-2 | Anti-Bovine CD200 monoclonal antibody | Bovine |
GM-Tg-equg-T81695-Ab-1/ GM-Tg-equg-T81695-Ab-2 | Anti-Equine CD200 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-T81695-Ab-1/ GM-Tg-hg-T81695-Ab-2; GM-Tg-rg-T81695-Ab-1/ GM-Tg-rg-T81695-Ab-2; GM-Tg-mg-T81695-Ab-1/ GM-Tg-mg-T81695-Ab-2; GM-Tg-cynog-T81695-Ab-1/ GM-Tg-cynog-T81695-Ab-2; GM-Tg-felg-T81695-Ab-1/ GM-Tg-felg-T81695-Ab-2; GM-Tg-cang-T81695-Ab-1/ GM-Tg-cang-T81695-Ab-2; GM-Tg-bovg-T81695-Ab-1/ GM-Tg-bovg-T81695-Ab-2; GM-Tg-equg-T81695-Ab-1/ GM-Tg-equg-T81695-Ab-2 |
Products Name | Anti-CD200 monoclonal antibody |
Format | mab |
Target Name | CD200 |
Protein Sub-location | Transmembrane Protein |
Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-CD200 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Biosimilar | GMP-Bios-ab-504 | Pre-Made Samalizumab biosimilar, Whole mAb, Anti-CD200 Antibody: Anti-MRC/MOX1/MOX2/OX-2 therapeutic antibody |
Target Antigen | Products Developing | Multi-species OX2G/ CD200/ MOX1 VLP (virus-like particle) (Products Developing) |
ORF Viral Vector | pGMAP000585 | Human CD200 Adenovirus plasmid |
ORF Viral Vector | vGMAP000585 | Human CD200 Adenovirus particle |
ORF Viral Vector | pGMLV000200 | human CD200 Lentivirus plasmid |
ORF Viral Vector | vGMLV000200 | human CD200 Lentivirus particle |
ORF Viral Vector | pGMLPm000698 | mouse Cd200 Lentivirus plasmid |
ORF Viral Vector | vGMLPm000698 | mouse Cd200 Lentivirus particle |
Target information
Target ID | GM-T81695 |
Target Name | CD200 |
Gene ID | 4345,17470,24560,708110,607499,101096094,534910 |
Gene Symbol and Synonyms | CD200,Cspmo2,MOX1,MOX2,MRC,MRCOX2,OX-2,OX2 |
Uniprot Accession | P41217,P04218 |
Uniprot Entry Name | OX2G_HUMAN,OX2G_RAT |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target, Immuno-oncology Target, INN Index |
Disease | Cancer |
Gene Ensembl | ENSG00000091972 |
Target Classification | Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA) |
The target: CD200, gene name: CD200, also named as MOX1, MOX2, MRC, OX-2. This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.