Anti-CATG/ CTSG/ CG monoclonal antibody
Anti-CATG/ CTSG/ CG antibody for FACS & in-vivo assay
Go to CTSG/CTSG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-T86385-Ab-1/ GM-Tg-hg-T86385-Ab-2 | Anti-Human CTSG monoclonal antibody | Human |
GM-Tg-rg-T86385-Ab-1/ GM-Tg-rg-T86385-Ab-2 | Anti-Rat CTSG monoclonal antibody | Rat |
GM-Tg-mg-T86385-Ab-1/ GM-Tg-mg-T86385-Ab-2 | Anti-Mouse CTSG monoclonal antibody | Mouse |
GM-Tg-cynog-T86385-Ab-1/ GM-Tg-cynog-T86385-Ab-2 | Anti-Cynomolgus/ Rhesus macaque CTSG monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-T86385-Ab-1/ GM-Tg-felg-T86385-Ab-2 | Anti-Feline CTSG monoclonal antibody | Feline |
GM-Tg-cang-T86385-Ab-1/ GM-Tg-cang-T86385-Ab-2 | Anti-Canine CTSG monoclonal antibody | Canine |
GM-Tg-bovg-T86385-Ab-1/ GM-Tg-bovg-T86385-Ab-2 | Anti-Bovine CTSG monoclonal antibody | Bovine |
GM-Tg-equg-T86385-Ab-1/ GM-Tg-equg-T86385-Ab-2 | Anti-Equine CTSG monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-T86385-Ab-1/ GM-Tg-hg-T86385-Ab-2; GM-Tg-rg-T86385-Ab-1/ GM-Tg-rg-T86385-Ab-2; GM-Tg-mg-T86385-Ab-1/ GM-Tg-mg-T86385-Ab-2; GM-Tg-cynog-T86385-Ab-1/ GM-Tg-cynog-T86385-Ab-2; GM-Tg-felg-T86385-Ab-1/ GM-Tg-felg-T86385-Ab-2; GM-Tg-cang-T86385-Ab-1/ GM-Tg-cang-T86385-Ab-2; GM-Tg-bovg-T86385-Ab-1/ GM-Tg-bovg-T86385-Ab-2; GM-Tg-equg-T86385-Ab-1/ GM-Tg-equg-T86385-Ab-2 |
Products Name | Anti-CTSG monoclonal antibody |
Format | mab |
Target Name | CTSG |
Protein Sub-location | Transmembrane Protein |
Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-CTSG benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | Products Developing | Multi-species CATG/ CTSG/ CG VLP (virus-like particle) (Products Developing) |
ORF Viral Vector | pGMAP000076 | Human CTSG Adenovirus plasmid |
ORF Viral Vector | vGMAP000076 | Human CTSG Adenovirus particle |
ORF Viral Vector | pGMLPm004318 | mouse Ctsg Lentivirus plasmid |
ORF Viral Vector | vGMLPm004318 | mouse Ctsg Lentivirus particle |
Target information
Target ID | GM-T86385 |
Target Name | CTSG |
Gene ID | 1511,13035,716440,106559147,101098719 |
Gene Symbol and Synonyms | CATG,CG,CTSG,VSP |
Uniprot Accession | P08311 |
Uniprot Entry Name | CATG_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target, Diagnostics Biomarker |
Disease | N/A |
Gene Ensembl | ENSG00000100448 |
Target Classification | N/A |
The target: CTSG, gene name: CTSG, also named as CATG, CG. The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Sep 2014].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.