Anti-CATG/ CTSG/ CG monoclonal antibody

Anti-CATG/ CTSG/ CG antibody for FACS & in-vivo assay

Target products collectionGo to CTSG/CTSG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-T86385-Ab-1/ GM-Tg-hg-T86385-Ab-2Anti-Human CTSG monoclonal antibodyHuman
GM-Tg-rg-T86385-Ab-1/ GM-Tg-rg-T86385-Ab-2Anti-Rat CTSG monoclonal antibodyRat
GM-Tg-mg-T86385-Ab-1/ GM-Tg-mg-T86385-Ab-2Anti-Mouse CTSG monoclonal antibodyMouse
GM-Tg-cynog-T86385-Ab-1/ GM-Tg-cynog-T86385-Ab-2Anti-Cynomolgus/ Rhesus macaque CTSG monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-T86385-Ab-1/ GM-Tg-felg-T86385-Ab-2Anti-Feline CTSG monoclonal antibodyFeline
GM-Tg-cang-T86385-Ab-1/ GM-Tg-cang-T86385-Ab-2Anti-Canine CTSG monoclonal antibodyCanine
GM-Tg-bovg-T86385-Ab-1/ GM-Tg-bovg-T86385-Ab-2Anti-Bovine CTSG monoclonal antibodyBovine
GM-Tg-equg-T86385-Ab-1/ GM-Tg-equg-T86385-Ab-2Anti-Equine CTSG monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-T86385-Ab-1/ GM-Tg-hg-T86385-Ab-2; GM-Tg-rg-T86385-Ab-1/ GM-Tg-rg-T86385-Ab-2;
GM-Tg-mg-T86385-Ab-1/ GM-Tg-mg-T86385-Ab-2; GM-Tg-cynog-T86385-Ab-1/ GM-Tg-cynog-T86385-Ab-2;
GM-Tg-felg-T86385-Ab-1/ GM-Tg-felg-T86385-Ab-2; GM-Tg-cang-T86385-Ab-1/ GM-Tg-cang-T86385-Ab-2;
GM-Tg-bovg-T86385-Ab-1/ GM-Tg-bovg-T86385-Ab-2; GM-Tg-equg-T86385-Ab-1/ GM-Tg-equg-T86385-Ab-2
Products NameAnti-CTSG monoclonal antibody
Formatmab
Target NameCTSG
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CTSG benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CATG/ CTSG/ CG VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMAP000076Human CTSG Adenovirus plasmid
    ORF Viral VectorvGMAP000076Human CTSG Adenovirus particle
    ORF Viral VectorpGMLPm004318mouse Ctsg Lentivirus plasmid
    ORF Viral VectorvGMLPm004318mouse Ctsg Lentivirus particle


    Target information

    Target IDGM-T86385
    Target NameCTSG
    Gene ID1511,13035,716440,106559147,101098719
    Gene Symbol and SynonymsCATG,CG,CTSG,VSP
    Uniprot AccessionP08311
    Uniprot Entry NameCATG_HUMAN
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target, Diagnostics Biomarker
    DiseaseN/A
    Gene EnsemblENSG00000100448
    Target ClassificationN/A

    The target: CTSG, gene name: CTSG, also named as CATG, CG. The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Sep 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.