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Anti-LGUL/ GLO1/ GLOD1 monoclonal antibody
Anti-LGUL/ GLO1/ GLOD1 antibody for FACS & in-vivo assay
Go to GLO1/GLO1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T88285-Ab-1/ GM-Tg-hg-T88285-Ab-2 | Anti-Human GLO1 monoclonal antibody | Human |
| GM-Tg-rg-T88285-Ab-1/ GM-Tg-rg-T88285-Ab-2 | Anti-Rat GLO1 monoclonal antibody | Rat |
| GM-Tg-mg-T88285-Ab-1/ GM-Tg-mg-T88285-Ab-2 | Anti-Mouse GLO1 monoclonal antibody | Mouse |
| GM-Tg-cynog-T88285-Ab-1/ GM-Tg-cynog-T88285-Ab-2 | Anti-Cynomolgus/ Rhesus macaque GLO1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T88285-Ab-1/ GM-Tg-felg-T88285-Ab-2 | Anti-Feline GLO1 monoclonal antibody | Feline |
| GM-Tg-cang-T88285-Ab-1/ GM-Tg-cang-T88285-Ab-2 | Anti-Canine GLO1 monoclonal antibody | Canine |
| GM-Tg-bovg-T88285-Ab-1/ GM-Tg-bovg-T88285-Ab-2 | Anti-Bovine GLO1 monoclonal antibody | Bovine |
| GM-Tg-equg-T88285-Ab-1/ GM-Tg-equg-T88285-Ab-2 | Anti-Equine GLO1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-T88285-Ab-1/ GM-Tg-hg-T88285-Ab-2; GM-Tg-rg-T88285-Ab-1/ GM-Tg-rg-T88285-Ab-2; GM-Tg-mg-T88285-Ab-1/ GM-Tg-mg-T88285-Ab-2; GM-Tg-cynog-T88285-Ab-1/ GM-Tg-cynog-T88285-Ab-2; GM-Tg-felg-T88285-Ab-1/ GM-Tg-felg-T88285-Ab-2; GM-Tg-cang-T88285-Ab-1/ GM-Tg-cang-T88285-Ab-2; GM-Tg-bovg-T88285-Ab-1/ GM-Tg-bovg-T88285-Ab-2; GM-Tg-equg-T88285-Ab-1/ GM-Tg-equg-T88285-Ab-2 |
| Products Name | Anti-GLO1 monoclonal antibody |
| Format | mab |
| Target Name | GLO1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-GLO1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species LGUL/ GLO1/ GLOD1 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP004608 | human GLO1 Lentivirus particle |
| ORF Viral Vector | pGMLP004608 | human GLO1 Lentivirus plasmid |
| ORF Viral Vector | pGMLV000001 | rat Glo1 Lentivirus plasmid |
| ORF Viral Vector | pGMLV000844 | house mouse Glo1 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm001072 | mouse Glo1 Lentivirus plasmid |
| ORF Viral Vector | vGMLV000001 | rat Glo1 Lentivirus particle |
| ORF Viral Vector | vGMLV000844 | house mouse Glo1 Lentivirus particle |
| ORF Viral Vector | vGMLPm001072 | mouse Glo1 Lentivirus particle |
Target information
| Target ID | GM-T88285 |
| Target Name | GLO1 |
| Gene ID | 2739,109801,294320,719518,474894,101085123,540335,100065189 |
| Gene Symbol and Synonyms | 0610009E22Rik,1110008E19Rik,2510049H23Rik,Glo-1,Glo-1r,Glo-1s,GLO1,Glo1-r,Glo1-s,GLOD1,GLY1,GLYI,HEL-S-74,Qglo |
| Uniprot Accession | Q04760,Q6P7Q4 |
| Uniprot Entry Name | LGUL_HUMAN,LGUL_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target |
| Disease | Breast Cancer |
| Gene Ensembl | ENSG00000124767 |
| Target Classification | N/A |
The target: GLO1, gene name: GLO1, also named as GLOD1, GLYI, HEL-S-74. The enzyme encoded by this gene is responsible for the catalysis and formation of S-lactoyl-glutathione from methylglyoxal condensation and reduced glutatione. Glyoxalase I is linked to HLA and is localized to 6p21.3-p21.1, between HLA and the centromere. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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